Dehydrotumulosic acid

Cat. No.: HY-N2499 Purity: 99.67%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body.

For research use only. We do not sell to patients.

Dehydrotumulosic acid Chemical Structure

CAS No. : 6754-16-1

Size	Price	Stock	Quantity
1 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Dehydrotumulosic acid:

Dehydrotumulosic acid (Standard) Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	> 40 μM Compound: 10	Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay	[PMID: 27808511]
HL-60	IC₅₀	> 40 μM Compound: 10	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 27808511]
K562	IC₅₀	> 40 μM Compound: 10	Antiproliferative activity against human K562 cells after 72 hrs by MTT assay Antiproliferative activity against human K562 cells after 72 hrs by MTT assay	[PMID: 27808511]
MOLT-4	IC₅₀	> 40 μM Compound: 10	Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay	[PMID: 27808511]

Molecular Weight

484.71

Formula

C₃₁H₄₈O₄

CAS No.

6754-16-1

Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@@]([C@]([C@H](C(O)=O)CCC(C(C)C)=C)([H])[C@H](O)C1)(CC=C3C2=CC[C@]4([H])[C@@]3(CC[C@H](O)C4(C)C)C)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (68.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0631 mL	10.3154 mL	20.6309 mL
5 mM	0.4126 mL	2.0631 mL	4.1262 mL
10 mM	0.2063 mL	1.0315 mL	2.0631 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.67%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (250 KB) HNMR (303 KB) LCMS (89 KB)

Handling Instructions (2659 KB)

References

[1]. Song Z, et al. The isolation, identification and determination of dehydrotumulosic acid in Poria cocos. Anal Sci. 2002 May;18(5):529-31. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0631 mL	10.3154 mL	20.6309 mL	51.5772 mL
	5 mM	0.4126 mL	2.0631 mL	4.1262 mL	10.3154 mL
	10 mM	0.2063 mL	1.0315 mL	2.0631 mL	5.1577 mL
	15 mM	0.1375 mL	0.6877 mL	1.3754 mL	3.4385 mL
	20 mM	0.1032 mL	0.5158 mL	1.0315 mL	2.5789 mL
	25 mM	0.0825 mL	0.4126 mL	0.8252 mL	2.0631 mL
	30 mM	0.0688 mL	0.3438 mL	0.6877 mL	1.7192 mL
	40 mM	0.0516 mL	0.2579 mL	0.5158 mL	1.2894 mL
	50 mM	0.0413 mL	0.2063 mL	0.4126 mL	1.0315 mL
	60 mM	0.0344 mL	0.1719 mL	0.3438 mL	0.8596 mL