2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. (±)-Hexanoylcarnitine chloride

(±)-Hexanoylcarnitine chloride  (Synonyms: DL-Hexanoylcarnitine chloride)

Cat. No.: HY-100978 Purity: ≥98.0%
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(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways.

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(±)-Hexanoylcarnitine chloride Chemical Structure

(±)-Hexanoylcarnitine chloride Chemical Structure

CAS No. : 6920-35-0

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5 mg USD 35 In-stock
10 mg USD 55 In-stock
25 mg USD 105 In-stock
50 mg USD 170 In-stock
100 mg USD 270 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (±)-Hexanoylcarnitine chloride:

(±)-Hexanoylcarnitine chloride Related Antibodies

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Description

(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways[1][2].

Molecular Weight

295.80

Formula

C13H26ClNO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (845.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3807 mL 16.9033 mL 33.8066 mL
5 mM 0.6761 mL 3.3807 mL 6.7613 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.3807 mL 16.9033 mL 33.8066 mL 84.5166 mL
5 mM 0.6761 mL 3.3807 mL 6.7613 mL 16.9033 mL
10 mM 0.3381 mL 1.6903 mL 3.3807 mL 8.4517 mL
15 mM 0.2254 mL 1.1269 mL 2.2538 mL 5.6344 mL
20 mM 0.1690 mL 0.8452 mL 1.6903 mL 4.2258 mL
25 mM 0.1352 mL 0.6761 mL 1.3523 mL 3.3807 mL
30 mM 0.1127 mL 0.5634 mL 1.1269 mL 2.8172 mL
40 mM 0.0845 mL 0.4226 mL 0.8452 mL 2.1129 mL
50 mM 0.0676 mL 0.3381 mL 0.6761 mL 1.6903 mL
60 mM 0.0563 mL 0.2817 mL 0.5634 mL 1.4086 mL
80 mM 0.0423 mL 0.2113 mL 0.4226 mL 1.0565 mL
100 mM 0.0338 mL 0.1690 mL 0.3381 mL 0.8452 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(±)-Hexanoylcarnitine chloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-Hexanoylcarnitine6920-35-0DL-HexanoylcarnitineEndogenous Metabolitefatty acid metabolitefatty acidsbiomarkerskeletal muscle toxicityrectus femoris muscleprediction of all-cause mortalitynovel pathogenic pathwaysInhibitorinhibitorinhibit

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