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Abivertinib maleate dihydrate

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-168427
    Avitinib maleate dihydrate

    Abivertinib maleate dihydrate; AC0010 maleate dihydrate

    		 EGFR Btk Apoptosis Cancer
    Avitinib (Abivertinib) maleate dihydrate is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib maleate dihydrate is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib maleate dihydrate shows anticancer effects .
    Avitinib maleate dihydrate

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