Search Result

Results for "

Chirality

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Adrenergic Receptor (1) Amino Acid Derivatives (1) Amyloid-β (2) Antibiotic (1) Apoptosis (1) Biochemical Assay Reagents (16) Btk (1) CCR (1) DNA/RNA Synthesis (1) E1/E2/E3 Enzyme (1) Endogenous Metabolite (7) Ferroptosis (1) Fungal (4) Glutathione S-transferase (1) Integrin (1) Isotope-Labeled Compounds (2) JAK (1) MDM-2/p53 (1) Phospholipase (2) RIP kinase (1) Stearoyl-CoA Desaturase (SCD) (2) γ-secretase (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (4) Endocrinology (1) Infection (7) Inflammation/Immunology (5) Metabolic Disease (4)
Click Chemistry:	Azide (2)
Oligonucleotides:	Nucleotides and their Analogs (1) Phospholipids (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W002502

(DHQ)2PHAL Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine; (DHQ)2PHAL	Biochemical Assay Reagents	Others
(DHQ)2PHAL (Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine) can be utilized as chiral ligand in asymmetric dihydroxylation .

HY-I0259

8-Amino-2-naphthol	Biochemical Assay Reagents	Others
8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .

HY-10193A

(1R)-AZD-1480	JAK	Cancer
(1R)-AZD-1480 is the (1R) chiral isomer of AZD-1480, an ATP competitive JAK1 and JAK2 inhibitor .

HY-136369

Ethofumesate	Others	Others
Ethofumesate, a chiral herbicide, acts by inhibiting mitosis and reducing photosynthesis and plant respiration .

HY-Y1126

(2S)-2-Pyrrolidinemethanol (S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol	Biochemical Assay Reagents	Others
(2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-W098280

Phenylglycine methyl ester	Biochemical Assay Reagents	Others
Phenylglycine methyl ester is a chiral anisotropic reagent. Phenylglycine methyl ester can be used for absolute configuration determination of various chiral carboxylic acids .

HY-116653

Flurtamone	Stearoyl-CoA Desaturase (SCD)	Others
Flurtamone is a chiral herbicide with acute toxicity levels to Selenastrum capricornutum .

HY-116653R

Flurtamone (Standard)	Stearoyl-CoA Desaturase (SCD)	Others
Flurtamone (Standard) is the analytical standard of Flurtamone. This product is intended for research and analytical applications. Flurtamone is a chiral herbicide with acute toxicity levels to Selenastrum capricornutum .

HY-W017610

(R)-1-Phenyl-2-propanol	Others	Others
(R)-1-Phenyl-2-propanol is a chiral alcohol. (R)-1-Phenyl-2-propanol can be converted from (S)-1-phenyl-2-propanol .

HY-136369R

Ethofumesate (Standard)	Others	Others
Ethofumesate (Standard) is the analytical standard of Ethofumesate. This product is intended for research and analytical applications. Ethofumesate, a chiral herbicide, acts by inhibiting mitosis and reducing photosynthesis and plant respiration .

HY-Y1126R

(2S)-2-Pyrrolidinemethanol (Standard)	Biochemical Assay Reagents	Others
(2S)-2-Pyrrolidinemethanol (Standard) is the analytical standard of (2S)-2-Pyrrolidinemethanol. This product is intended for research and analytical applications. (2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-B1871

Metolachlor	Others	Others
Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .

HY-B1871R

Metolachlor (Standard)	Others	Others
Metolachlor (Standard) is the analytical standard of Metolachlor. This product is intended for research and analytical applications. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .

HY-N9022

(S)-1-(4-Hydroxy-2,2-dimethylchroman-6-yl)ethanone	Others	Others
(S)-1-(4-Hydroxy-2,2-dimethylchroman-6-yl)ethanone is an enantiopure chiral alcohol. Stereoselective reduction of prochiral ketones is studied by using both cell cultures and wild tissues of various endemic plant species .

HY-123622

CYMAL-5, 98% (TLC)	Biochemical Assay Reagents	Others
CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .

HY-125630

Decacyclene	Others	Others
Decacyclene is a large polycyclic aromatic hydrocarbon with a triple symmetry. Decacyclene is a three-blade molecular propeller in the solid state, and crystal structure analysis shows that the molecule has a non-planar twisted form, and the crystal is chiral, which may correspond to the enantiomers of the Decacyclene propeller. Decacyclene can be used for research in chemical synthesis and materials science .

HY-149727

β2AR agonist 2	Adrenergic Receptor	Metabolic Disease
β2AR agonist 2(compound 8a) is a β₂ -Adrenergic receptor (β₂AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D) .

HY-14507

YK-4-279 5+ Cited Publications	DNA/RNA Synthesis Apoptosis	Cancer
YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer .

HY-114769

Beflubutamid UBH 820	Others	Others
Beflubutamid is a chiral soil herbicide against dicotyledonous weeds in cereals .

HY-W062695

(R)-Acalabrutinib (R)-ACP-196	Btk	Cancer
(R)-Acalabrutinib ((R)-ACP-196) is the enantiomer of Acalabrutinib (HY-17600). (R)-Acalabrutinib is an inhibitor for Bruton’s tyrosine kinase (BTK) .

HY-W351380

(-)-Anicyphos	Others
(-)-Anicyphos is a chiral catalyst with the activity of promoting the selectivity of specific reactions. (-)-Anicyphos is often used to synthesize complex chiral molecules in organic synthesis and shows excellent catalytic performance. By adjusting the reaction conditions, (-)-Anicyphos can significantly improve the stereospecificity of the product, providing an effective strategy for compound development.

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Amino Acid Derivatives	Others
N-Acetyl-R-leucine is an amino protecting group N-substituted chiral amino acid .

HY-N9761

Murrayanine	Others	Others
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .

HY-W425671

N-Isobutyryl-L-cysteine	Others	Others
N-Isobutyryl-L-cysteine serves as a chiral derivatizing agent that is extensively utilized for the separation of amino acid enantiomers.

HY-40135

L-Hydroxyproline (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid	Endogenous Metabolite	Others
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-139166

N-Palmitoyl-L-aspartate N-Palmitoyl aspartic acid	Others	Others
N-Palmitoyl-L-aspartate (N-Palmitoyl aspartic acid) is a chiral compound with properties of the aggregates formed in aqueous solution .

HY-I0606B

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde	Others
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a chiral molecule with potential chiral catalytic activity. It can be used as an intermediate in organic synthesis and plays a key role in the construction of complex molecular systems. This compound has also been used to develop new compound carriers and exhibits good biocompatibility.

HY-W017206

1-Phenyl-2-nitropropene	Others	Others
1-Phenyl-2-nitropropene is the reduction product of acetophenone and can be used to prepare chiral amine compounds .

HY-70027

*p53 and MDM2 proteins-interaction-inhibitor (chiral)*	MDM-2/p53 E1/E2/E3 Enzyme	Cancer
p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.

HY-114769R

Beflubutamid (Standard)	Others	Others
Beflubutamid (Standard) is the analytical standard of Beflubutamid. This product is intended for research and analytical applications. Beflubutamid is a chiral soil herbicide against dicotyledonous weeds in cereals .

HY-Y1422I

Lipase AK	Others	Others
Lipase AK comes from Pseudomonas fluorescens and shows good applicability in ester synthesis of food industry, the biofuel synthesis, the synthesis of enantiomeric pure chiral drugs and so on .

HY-24312

AD-mix-α	Biochemical Assay Reagents	Others
AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.

HY-40135S

L-Hydroxyproline-d3	Isotope-Labeled Compounds Endogenous Metabolite	Others
L-Hydroxyproline-d₃ is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-111487

α-Methylacyl-CoA racemase 1	Others	Metabolic Disease Cancer
α-methylacyl-CoA racemase 1 is an enzyme that catalyzes a key chiral inversion step in the metabolism of branched-chain fatty acids, and used as a maker in prostate and other cancer.

HY-103028A

GSK963 1 Publications Verification	RIP kinase	Others
GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC₅₀ of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro .

HY-120460

8(R)-HETE 8(R)-Hydroxyeicosatetraenoic acid	Others	Inflammation/Immunology
8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish. Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC retention times to published results.

HY-W002878

TsDPEN	Biochemical Assay Reagents	Others
TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .

HY-161249

Vanin-1-IN-4	Others	Inflammation/Immunology
Vanin-1-IN-4 (compound (S)-1) is vanin-1 inhibitor with a chiral methyl substituent, with profils as potent drug-candidate but exist as an amorphous solid .

HY-40135R

L-Hydroxyproline (Standard)	Endogenous Metabolite	Others
L-Hydroxyproline (Standard) is the analytical standard of L-Hydroxyproline. This product is intended for research and analytical applications. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-W075744

SK-J002-1n	Others
SK-J002-1n is a highly efficient catalyst with excellent cross-coupling reaction activity. SK-J002-1n is widely used in organic synthesis to construct complex molecular structures. The chiral properties of SK-J002-1n make it play an important role in the pharmaceutical industry and provide support for the synthesis of chiral compounds. SK-J002-1n can significantly improve the conversion efficiency and is an important component of transition metal catalysts.

HY-117089

Tetraconazole	Fungal	Infection
Tetraconazole, a chiral triazole fungicide, is widely used for the prevention of plant disease in wheat fields . Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds .

HY-17520

Penthiopyrad MTF-753	Fungal	Infection
Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .

HY-W012618

1-Phenyl-1-propanol	Others	Others
1-Phenyl-1-propanol is used as a chiral building block and synthetic intermediate in the pharmaceutical industries. 1-Phenyl-1-propanol is an intermediate of anti-depressant agent Fluoxetine .

HY-117068

(R)-Bromoenol lactone (R,E)-Bromoenol lactone	Phospholipase	Others
(R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC₅₀ of approximately 0.6 µM .

HY-B1871S

Metolachlor-d6	Isotope-Labeled Compounds	Others
Metolachlor-d₆ is the deuterium labeled Metolachlor[1]. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[2][3].

HY-112792A

(1S)-CCR2 antagonist 1	CCR	Endocrinology
(1S)-CCR2 antagonist 1 is a left-handed chiral body of CCR2 antagonist 1 (HY-112792). CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a K_i of 2.4 nM .

HY-117089R

Tetraconazole (Standard)	Fungal	Infection
Tetraconazole (Standard) is the analytical standard of Tetraconazole. This product is intended for research and analytical applications. Tetraconazole, a chiral triazole fungicide, is widely used for the prevention of plant disease in wheat fields . Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds .

HY-120986

(S)-Bromoenol lactone (S)-BEL; (S,E)-Bromoenol lactone	Phospholipase	Inflammation/Immunology
(S)-Bromoenol lactone ((S)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase A₂β (iPLA₂β) that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with an IC₅₀ of 2 µM .

HY-17520R

Penthiopyrad (Standard)	Fungal	Infection
Penthiopyrad (Standard) is the analytical standard of Penthiopyrad. This product is intended for research and analytical applications. Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .

HY-Y1131

Ethyl (R)-3-hydroxybutyrate Ethyl (R)-3-hydroxybutanoate	Biochemical Assay Reagents	Others
Ethyl (R)-3-hydroxybutyrate is an organic compound commonly used as a starting material for chiral chemical synthesis. It can be used in the preparation of medicines, spices, fine chemicals and food additives, etc., and is widely used in medicine, cosmetics and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions

Cat. No.	Product Name

HY-L903

3D Diverse Fragment Library

5,400 compounds

Fragment-based drug discovery (FBDD) is well suited for discovering both drug leads and chemical probes of protein function. 3-dimensionality (3D) diversity is pivotal because the molecular shape is one of the most important factors in molecular recognition by a biomolecule. There is a developing appreciation that 3D fragments could offer opportunities that are not provided by 2D fragments.

MCE 3D Diverse Fragment Library consists of 5,400 non-flat fragment-like molecules (average Fsp3 value 0.58). More than 4,700 fragment compounds contain at least one chiral center in the structure. The key concepts that underlie the library design were 3D shape, structural diversity, reactive functionality and fragment-like. This 3D Diverse Fragment Library brings higher fragment hit optimization and increases the likelihood to find innovative hits in FBDD.

HY-L0120V

Asinex BioDesign Library

170,269 compounds

“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.

Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).

Cat. No.	Product Name	Type

HY-W002502

(DHQ)2PHAL Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine; (DHQ)2PHAL	Biochemical Assay Reagents
(DHQ)2PHAL (Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine) can be utilized as chiral ligand in asymmetric dihydroxylation .

HY-I0259

8-Amino-2-naphthol	Biochemical Assay Reagents
8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .

HY-Y1126

(2S)-2-Pyrrolidinemethanol (S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol	Biochemical Assay Reagents
(2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-123622

CYMAL-5, 98% (TLC)

Surfactants

CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .

HY-24312

AD-mix-α

Biochemical Assay Reagents

AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.

HY-Y1131

Ethyl (R)-3-hydroxybutyrate Ethyl (R)-3-hydroxybutanoate	Drug Delivery
Ethyl (R)-3-hydroxybutyrate is an organic compound commonly used as a starting material for chiral chemical synthesis. It can be used in the preparation of medicines, spices, fine chemicals and food additives, etc., and is widely used in medicine, cosmetics and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions

HY-W012885

(S)-Methyl 3-hydroxybutanoate

Biochemical Assay Reagents

(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.

HY-W093149

(-)-Menthyloxyacetic acid	Biochemical Assay Reagents
(-)-Menthyloxyacetic acid can be used as a chiral resolving agent .

HY-Y1126R

(2S)-2-Pyrrolidinemethanol (Standard)

Biochemical Assay Reagents

(2S)-2-Pyrrolidinemethanol (Standard) is the analytical standard of (2S)-2-Pyrrolidinemethanol. This product is intended for research and analytical applications. (2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-W002878

TsDPEN	Biochemical Assay Reagents
TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .

HY-75920

Inhoffen Lythgoe diol

Biochemical Assay Reagents

Inhoffen Lythgoe diol is an organic molecule commonly used in chiral selective reactions in organic synthesis. It can be used as a catalyst and a ligand, and has a wide range of applications in the preparation of nitrogen- and sulfur-containing natural products, pharmaceuticals, and material science. Inhoffen Lythgoe diol plays a very important role in the field of asymmetric synthesis. Although it has no direct medical application, it plays an important role in the production and research of many important chemicals.

HY-75070

(+)-1-(1-Naphthyl)ethylamine

Biochemical Assay Reagents

(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

HY-W010394

Methyl 3-oxopentanoate

Drug Delivery

Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.

HY-W010507

(R)-Methyl 3-hydroxybutanoate

Methyl (R)-(-)-3-hydroxybutyrate

Drug Delivery

(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.

HY-W142618

D-Glucal

Carbohydrates

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Microorganisms Source classification	Amino Acid Derivatives
N-Acetyl-R-leucine is an amino protecting group N-substituted chiral amino acid .

HY-40135

L-Hydroxyproline (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid	Alkaloids Structural Classification Immune System Disorder Pyrrole Alkaloids Classification of Application Fields Source classification Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-N0548

α-Angelica lactone 2 Publications Verification	Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Cancer	Glutathione S-transferase
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

HY-N9022

(S)-1-(4-Hydroxy-2,2-dimethylchroman-6-yl)ethanone	Natural Products Source classification Plants Compositae Tephrosia purpurea (L.) Pers.	Others
(S)-1-(4-Hydroxy-2,2-dimethylchroman-6-yl)ethanone is an enantiopure chiral alcohol. Stereoselective reduction of prochiral ketones is studied by using both cell cultures and wild tissues of various endemic plant species .

HY-N9761

Murrayanine	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Rutaceae Murraya koenigii (L.) Spreng Plants	Others
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .

HY-40135R

L-Hydroxyproline (Standard)	Alkaloids Structural Classification Immune System Disorder Pyrrole Alkaloids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
L-Hydroxyproline (Standard) is the analytical standard of L-Hydroxyproline. This product is intended for research and analytical applications. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-N12970

14S(15R)-EET	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .

Cat. No.	Product Name	Chemical Structure

HY-40135S

L-Hydroxyproline-d3
L-Hydroxyproline-d₃ is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-B1871S

Metolachlor-d6
Metolachlor-d₆ is the deuterium labeled Metolachlor[1]. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[2][3].

Cat. No.	Product Name		Classification

HY-151702A

(2S)-N3-IsoSer (DCHA)		Azide
(2S)-N3-IsoSer DCHA is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151702

(2S)-N3-IsoSer		Azide
(2S)-N3-IsoSer is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-F0003

NADPH tetrasodium salt 5+ Cited Publications		Nucleotides and their Analogs
NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. The demand for NADPH tetrasodium salt is particularly high in proliferating cancer cells, where it acts as a cofactor for the synthesis of nucleotides, proteins, and fatty acids. NADPH tetrasodium salt is also essential for the neutralization of the dangerously high levels of reactive oxygen species (ROS) generated by increased metabolic activity. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis .

HY-120967A

(2S)-OMPT		Phospholipids
(2S)-OMPT triethylamine, a chiral oxirane derivative, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Chirality

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Natural
Products