1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. (S)-Bromoenol lactone

(S)-Bromoenol lactone  (Synonyms: (S)-BEL; (S,E)-Bromoenol lactone)

Cat. No.: HY-120986 Purity: ≥99.0%
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(S)-Bromoenol lactone ((S)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase A2β (iPLA2β) that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with an IC50 of 2 µM.

For research use only. We do not sell to patients.

(S)-Bromoenol lactone Chemical Structure

(S)-Bromoenol lactone Chemical Structure

CAS No. : 478288-94-7

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1 mg(3.15 mM * 1 mL in Methyl acetate) USD 310 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

(S)-Bromoenol lactone ((S)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase A2β (iPLA2β) that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with an IC50 of 2 µM[1].

IC50 & Target

PLA2

 

Molecular Weight

317.18

Formula

C16H13BrO2

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C1[C@H](C2=C3C=CC=CC3=CC=C2)CC/C(O1)=C\Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: ≥99.0%

References
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(S)-Bromoenol lactone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(S)-Bromoenol lactone
Cat. No.:
HY-120986
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