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  5. Murrayanine

Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis.

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Murrayanine Chemical Structure

Murrayanine Chemical Structure

CAS No. : 723-97-7

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Description

Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis[1].

Cellular Effect
Cell Line Type Value Description References
KB IC50
72.23 μM
Compound: 15
Cytotoxicity against human KB cells by resazurin microplate assay
Cytotoxicity against human KB cells by resazurin microplate assay
[PMID: 21302964]
NCI-H187 IC50
11.45 μM
Compound: 15
Cytotoxicity against human NCI-H187 by resazurin microplate assay
Cytotoxicity against human NCI-H187 by resazurin microplate assay
[PMID: 21302964]
Neutrophil IC50
3.5 μM
Compound: 21
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
[PMID: 24798144]
Neutrophil IC50
3.9 μM
Compound: 21
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
[PMID: 24798144]
Vero IC50
> 200 μM
Compound: 15
Cytotoxicity against african green monkey Vero cells by green fluorescent protein microplate assay
Cytotoxicity against african green monkey Vero cells by green fluorescent protein microplate assay
[PMID: 21302964]
Molecular Weight

225.24

Formula

C14H11NO2

CAS No.
SMILES

O=CC1=CC2=C(NC3=C2C=CC=C3)C(OC)=C1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Murrayanine
Cat. No.:
HY-N9761
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