1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. (R)-Bromoenol lactone

(R)-Bromoenol lactone  (Synonyms: (R,E)-Bromoenol lactone)

Cat. No.: HY-117068
Handling Instructions

(R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM.

For research use only. We do not sell to patients.

(R)-Bromoenol lactone Chemical Structure

(R)-Bromoenol lactone Chemical Structure

CAS No. : 478288-90-3

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Description

(R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM[1].

Molecular Weight

317.18

Formula

C16H13BrO2

CAS No.
SMILES

O=C1[C@@H](C2=C3C=CC=CC3=CC=C2)CC/C(O1)=C\Br

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(R)-Bromoenol lactone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(R)-Bromoenol lactone
Cat. No.:
HY-117068
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