TsDPEN 

TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions^[1][2].

366.48

C₂₁H₂₂N₂O₂S

144222-34-4

Solid

White to off-white

N[C@@H]([C@H](NS(C1=CC=C(C)C=C1)(=O)=O)C2=CC=CC=C2)C3=CC=CC=C3

Room temperature in continental US; may vary elsewhere.

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Hayes A, et al. The importance of 1, 2-anti-disubstitution in monotosylated diamine ligands for ruthenium (II)-catalysed asymmetric transfer hydrogenation. Tetrahedron: Asymmetry, 2004, 15(13): 2079-2084.

  [2]. Xu C, et al. Development of TsDPEN based imine-containing ligands for the copper-catalysed asymmetric Kinugasa reaction. RSC Adv. 2020 May 12;10(31):18107-18114.  [Content Brief]