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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

Cytosolic enzyme

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Fluorescent Dye

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116301
    CAY10502

    		Phospholipase Inflammation/Immunology
    CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases .
    CAY10502
  • HY-129225
    WRR139

    		Others Cancer
    WRR139 is a peptide vinyl sulfone involving in disease processes such as inflammation and cancer. WRR139 is also a cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1 inhibitor. WRR139 enhances Carfilzomib cytotoxicity against cancer cells .
    WRR139
  • HY-W006230
    Anthraflavic acid

    		Cytochrome P450 Cancer
    Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity inhibitor by virtue of its ability to inhibit both its microsomal and cytosolic activation pathways. Anthraflavic acid is a potent and specific cytochrome P-448 inhibitor activity an enzyme system closely associated with the activation of many chemical carcinogens .
    Anthraflavic acid
  • HY-128369
    Acid Yellow 36

    Metanil Yellow

    		 Cytochrome P450 Others
    Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .
    Acid Yellow 36
  • HY-E70377
    Cu/Zn Superoxide dismutase

    Cu/Zn SOD

    		 SOD Inflammation/Immunology Cancer
    Cu/Zn Superoxide dismutase (Cu/Zn SOD; SOD1) is a cytosolic copper-zinc dimer form of superoxide dismutase enzyme. Cu/Zn Superoxide dismutase has oxygen radical enzymatic dismutation .
    Cu/Zn Superoxide dismutase
  • HY-B1370E
    (R)-Hydroxychloroquine phosphate

    (R)-HCQ phosphate

    		 Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy Metabolic Disease
    (R)-Hydroxychloroquine ((R)-HCQ) phosphate is a (R)-isomer of Hydroxychloroquine (HY-W031727). (R)-Hydroxychloroquine inhibits the insulin metabolizing enzyme of cytosolic fraction of liver homogenates in healthy and diabetic rats .
    (R)-Hydroxychloroquine phosphate
  • HY-P2999
    Endo-β-N-acetylglucosaminidase

    ENGase

    		 Endogenous Metabolite Others
    Endo-β-N-acetylglucosaminidase (ENGase) is cytosolic deglycosylating enzyme that hydrolyzes the N-linked oligosaccharides. Endo-β-N-acetylglucosaminidase can be used for glycan analysis on glycoproteins and preparation of precursors for glycosylated compounds, is often used in biochemical studies .
    Endo-β-N-acetylglucosaminidase
  • HY-W1006754
    NNMT-IN-7

    		Amine N-methyltransferase Metabolic Disease
    NNMT-IN-7 (Compound 4e) is a NNMT inhibitor (IC50 = 505.7 µM). NNMT-IN-7 can be used in studies of metabolic and chronic diseases .
    NNMT-IN-7
  • HY-145751
    7α-Hydroxy-DHEA

    7α-Hydroxydehydroepiandrosterone; 3β,7α-Dihydroxy-Δ5-androsten-17-one

    		 Cytochrome P450 Mitochondrial Metabolism Metabolic Disease Cancer
    7α-Hydroxy-DHEA (7α-Hydroxydehydroepiandrosterone) is a 7α-hydroxylated metabolite of DHEA (HY-14650), catalyzed by intracellular steroid 7α-hydroxylases such as P450 2A1. 7α-Hydroxy-DHEA exhibits biological activity comparable to DHEA but does not convert into compounds with androgenic or estrogenic activity. It induces the activity of thermogenic enzymes such as mitochondrial sn-glycerol-3-phosphate dehydrogenase and cytosolic malic enzyme, enhancing heat production and reducing food utilization efficiency. As a more efficient and safer metabolite compared to DHEA, 7α-Hydroxy-DHEA holds potential for studies in the fields of obesity, metabolic diseases, and adrenal carcinoma .
    7α-Hydroxy-DHEA

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