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JH-VIII-49

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125001
    JH-VIII-49

    		CDK Ligands for Target Protein for PROTAC Cancer
    JH-VIII-49 (compound 10) is a potent and selective CDK8 inhibitor (IC50=16 nM) with excellent biological activity. JH-VIII-49 promotes CDK8 inhibition through its steroid backbone design. JH-VIII-49 can be used in the synthesis of PROTAC as a target protein ligand of JH-XI-10-02 (HY-111518) .
    JH-VIII-49

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