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Streptomyces sp

" in MedChemExpress (MCE) Product Catalog:

44

Inhibitors & Agonists

1

Peptides

30

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2936
    Sphingomyelin phosphodiesterase, Streptomyces sp.

    		Phospholipase Metabolic Disease
    Sphingomyelin phosphodiesterase, Streptomyces sp., a hydrolase, is involved in the sphingomyelin metabolism process. Sphingomyelin phosphodiesterase hydrolyzes the conversion of sphingomyelin to phosphocholine and ceramide. Sphingomyelin phosphodiesterase also plays an important role in cellular differentiation, various immune and inflammatory responses, and intracellular cholesterol trafficking and metabolism .
    Sphingomyelin phosphodiesterase, Streptomyces sp.
  • HY-E70328
    Alkalophilic Proteinase, Streptomyces sp

    		Endogenous Metabolite Others
    Alkalophilic Proteinase, Streptomyces sp is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
    Alkalophilic Proteinase, Streptomyces sp
  • HY-157017
    Julichrome Q3.5

    		Biochemical Assay Reagents Others
    Julichrome Q3.5 (Compound 4) is a bioherbicide that completely inhibits the growth of cabbage. Julichrome Q3.5 can be isolated from the supernatant extract of strain Streptomyces sp. NEAU-HV44 .
    Julichrome Q3.5
  • HY-113945
    Abbeymycin

    		Antibiotic Bacterial Infection
    Abbeymycin is an antibiotic derived from the actinobacterium Streptomyces sp. AB-999F-52. Abbeymycin is a specifically acting antibiotic with antimicrobial activity, primarily targeting anaerobic bacteria. Abbeymycin is employed in research concerning antibiotic discovery and screening .
    Abbeymycin
  • HY-N13017
    Bhimanone

    		Endogenous Metabolite Others
    Bhimanone is a bioinactive tetralone, which can be isolated from Streptomyces sp. .
    Bhimanone
  • HY-N13149
    Tetromycin C1

    		Antibiotic Bacterial Infection
    Tetromycin C1 is an antibiotic bactericide isolated from Streptomyces sp. .
    Tetromycin C1
  • HY-124163
    Epostatin

    		Dipeptidyl Peptidase Others
    Epostatin is a competitive dipeptidyl peptidase II (DPP-II) inhibitor with an IC50 of 0.96 μg/mL .
    Epostatin
  • HY-N12787
    T-Muurolol

    		Others Others
    T-Muurolol is a sesquiterpene and can be isolated from Streptomyces sp. M491 .
    T-Muurolol
  • HY-131054
    Cinerubin B

    		Antibiotic Bacterial Infection
    Cinerubin B, a glycosylated anthracycline antibiotic, is an anticancer agent from Streptomyces sp. SPB74 .
    Cinerubin B
  • HY-N11620
    Sadopeptins A

    		Proteasome Others
    Sadopeptins A is a nature product that could be isolated from Streptomyces sp. Sadopeptins A is a potent proteasome inhibitor .
    Sadopeptins A
  • HY-125458
    Iromycin A

    		NO Synthase Others
    Iromycin A is a potent inhibitor of nitric oxide synthases (NO synthase) that can be isolated from Streptomyces sp. .
    Iromycin A
  • HY-119246
    A-269A

    		Bacterial Antibiotic Infection
    A-269A is a streptothricin-like compound derived from Streptomyces sp. with antimicrobial activity .
    A-269A
  • HY-119025
    L 681176

    		Others Cardiovascular Disease
    L 681176 is an angiotensin-converting enzyme inhibitor that can be isolated from STREPTOMYCES sp. MA 5143a .
    L 681176
  • HY-129669
    Landomycin A

    		Others Infection
    Landomycin A is a notable antibiotic belonging to the angucycline class, characterized by its hexasaccharide structure, and is derived from Streptomyces sp.
    Landomycin A
  • HY-N11621
    Sadopeptins B

    		Proteasome Others
    Sadopeptins B is a nature product that could be isolated from Streptomyces sp. Sadopeptins B is a potent proteasome inhibitor .
    Sadopeptins B
  • HY-125410
    Promothiocin A

    		Endogenous Metabolite Infection
    Promothiocin A is a thiopeptide with tipA promoter inducing activity. Promothiocin A can be extracted from Streptomyces sp. SF2741 .
    Promothiocin A
  • HY-114585A
    Sperabillin A dihydrochloride

    		Glutathione S-transferase Others
    Sperabillin A (dihydrochloride)is new inhibitors ofglutathione S-transferaseisolated from the culture broth ofStreptomyces sp .
    Sperabillin A dihydrochloride
  • HY-N11415
    Aurachin SS

    		Antibiotic Bacterial Infection
    Aurachin SS is a nature product that could be isolated from Streptomyces sp. NA04227. Aurachin SS is an antibiotic and has antibacterial activity .
    Aurachin SS
  • HY-N12322
    Dihydrotetrodecamycin

    		Antibiotic Bacterial Infection
    Dihydrotetrodecamycin is an antibiotic that can be isolated from the fermentation broth of Streptomyces nashvillensis MJ885-mF8. Dihydrotetrodecamycin has MIC values of 50 mg/mL against both Pasteurella piscicida sp. 639 and P. piscicida sp. 6356 .
    Dihydrotetrodecamycin
  • HY-106338
    Polyketomycin

    		Bacterial ADC Cytotoxin Parasite Infection Cancer
    Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities .
    Polyketomycin
  • HY-111264
    Naphthomycin B

    		Antibiotic Bacterial Fungal Infection
    Naphthomycin B is an antibiotic, which is initially isolated from Streptomyces sp. Naphthomycin B exhibits antimicrobial activities against gram positive bacteria and many fungis .
    Naphthomycin B
  • HY-125653
    Kapurimycin A2

    		Antibiotic Bacterial Infection Cancer
    Kapurimycin A2 is an antitumor antibiotic that can be found in the culture of Streptomyces sp.. Kapurimycin A2 is an active against bacteria, particularly Gram-positive organisms .
    Kapurimycin A2
  • HY-N6738
    Bafilomycin B1

    		Bacterial Fungal Antibiotic Infection
    Bafilomycin B1 is a macrolide antibiotic isolated from Streptomyces sp, inhibits Gram-positive bacteria and fungi, and acts as an inhibitor of K +-dependent ATPase of E. coli .
    Bafilomycin B1
  • HY-119736
    Leptolstatin

    		Others Others
    Leptolstatin is an inhibitor of the progression of G1 and G2 phases of the mammalian cell cycle. Leptolstatin can be extracted from the fermentation broth of Streptomyces sp. SAM1595 .
    Leptolstatin
  • HY-12450
    Lomofungin

    Lomondomycin

    		 Antibiotic Bacterial Infection
    Lomofungin is a novel antibiotic produced by Streptomyces lomondensis sp.N . Lomofungin can inhibit MBNL1-CUG RNA binding. Lomofungin has antibacterial activity .
    Lomofungin
  • HY-129558
    UK-1

    		HCV Infection Cancer
    UK-1 is a cytotoxic metabolite from Streptomyces sp. 517-02 and exerts a wide spectrum of potent anticancer activities . UK-1 also inhibits HCV replication .
    UK-1
  • HY-125637
    Venturicidin B

    Aabomycin A2

    		 Antibiotic Fungal ATP Synthase Infection
    Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex .
    Venturicidin B
  • HY-121452
    Migrastatin

    		Others Cancer
    Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration .
    Migrastatin
  • HY-N10605
    Maniwamycin E

    		SARS-CoV Influenza Virus Infection
    Maniwamycin E is a maniwamycin derivative isolated from the culture extract of thermotolerant Streptomyces sp. JA74. Maniwamycin E shows antiviral activity against SARS-CoV-2 and influenza (H1N1) virus .
    Maniwamycin E
  • HY-125747
    Actinomycin X2
    1 Publications Verification

    Actinomycin V

    		 Bacterial Antibiotic Apoptosis Infection Cancer
    Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection .
    Actinomycin X2
  • HY-118331
    Kazusamycin B

    PD 124895; CL-1957E

    		 Antibiotic Infection Cancer
    Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer .
    Kazusamycin B
  • HY-119604
    Cafamycin

    		Antibiotic Bacterial Infection
    Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .
    Cafamycin
  • HY-163113
    Anticancer agent 180

    		Others Cancer
    Anticancer agent 180 (compound 4) is a secondary metabolite present in fungal strains and extracted through physical interaction with Streptomyces sp. Anticancer agent 180 has potential anti-tumor activity and can inhibit the migration of MDA-MB-231 breast cancer cells .
    Anticancer agent 180
  • HY-123095
    TS 155-2

    JBIR 100

    		 Antibiotic Bacterial Proton Pump Infection Inflammation/Immunology Endocrinology
    TS 155-2 (JBIR 100), an antimicrobial agent, is a Bafilomycin analogue and an antibiotic. TS 155-2 can be isolated from a culture of Streptomyces sp. TS 155-2 inhibits V-ATPase activity. V-ATPase is correlated with an increasing number of diseases such as osteopetrosis, male infertility and renal acidosis .
    TS 155-2
  • HY-121071
    Ascamycin

    		Bacterial Nucleoside Antimetabolite/Analog Antibiotic Infection
    Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively .
    Ascamycin
  • HY-19828
    Herboxidiene

    GEX1A

    		 DNA/RNA Synthesis Cancer
    Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .
    Herboxidiene
  • HY-130173
    Bafilomycin C1
    1 Publications Verification

    		 Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic Infection Cancer
    Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H +-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .
    Bafilomycin C1
  • HY-114798
    Rabelomycin

    		Antibiotic Bacterial NO Synthase Infection Neurological Disease
    Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM .
    Rabelomycin
  • HY-105463
    Saptomycin D

    		Antibiotic Bacterial Infection Cancer
    Saptomycin D is an antibiotic with antitumor activity isolated from the Streptomyces sp. HP530 strain. Saptomycin D exhibits potent inhibitory effects against Gram-positive bacteria, while demonstrating weaker inhibitory activities against certain Gram-negative bacteria and yeasts. Saptomycin D also displays remarkable antitumor properties. Saptomycin D is applicable in research within the field of oncology .
    Saptomycin D
  • HY-N13059
    Waldiomycin

    		Antibiotic Infection
    Waldiomycin is an antibiotic that can be isolated from Streptomyces sp. MK844-mF10 that has inhibitory effects on low GC-content Gram-positive bacteria. Waldiomycin inhibits the activity of WalK kinase by targeting its ATP-binding domain, thereby blocking the WalK/WalR signal transduction system, which plays a role in cell growth and division .
    Waldiomycin
  • HY-120721
    Lagunamycin

    		Lipoxygenase Cancer
    Lagunamycin is a 5-lipoxygenase inhibitor isolated from the culture medium of Streptomyces sp. AA0310. Lagunamycin has a significant inhibitory activity against rat 5-lipoxygenase with an IC50 value of 6.08 μM. Lagunamycin can effectively inhibit 5-lipoxygenase without causing lipid peroxidation, indicating that it has an effective inhibitory effect without causing side effects.
    Lagunamycin
  • HY-P1708
    Enopeptin A

    BRN 537924; NSC 657143

    		 Bacterial Infection
    Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC=25 μg/mL), and Gram-negative bacteria, including mutant forms of E. coli and P. aeruginosa (MICs=200 μg/mL); however, it is not inhibitory to fungi.
    Enopeptin A
  • HY-118043
    RK-1441B

    		Antibiotic Infection
    RK-1441B is an anti-phage antibiotic produced by Streptomyces sp. RK-1441 and belongs to the pyrrolo[1,4]benzodiazepine class. RK-1441B has antiphage activity but no significant antimicrobial activity against a supersusceptible E. coli strain to an antitumor antibiotic. RK-1441B is inactive in vitro and may be converted to the active form in the host organism. Its fellow antibiotic RK-1441A can form an adduct with guanine residues in the DNA chain to exert resistance .
    RK-1441B
  • HY-134090
    9-Methylstreptimidone

    Antibiotic TS 885; NSC 248958

    		 Bacterial Infection
    9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
    9-Methylstreptimidone

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