1. Metabolic Enzyme/Protease
  2. Lipoxygenase
  3. Lagunamycin

Lagunamycin is a 5-lipoxygenase inhibitor isolated from the culture medium of Streptomyces sp. AA0310. Lagunamycin has a significant inhibitory activity against rat 5-lipoxygenase with an IC50 value of 6.08 μM. Lagunamycin can effectively inhibit 5-lipoxygenase without causing lipid peroxidation, indicating that it has an effective inhibitory effect without causing side effects.

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Lagunamycin Chemical Structure

Lagunamycin Chemical Structure

CAS No. : 150693-65-5

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Description

Lagunamycin is a 5-lipoxygenase inhibitor isolated from the culture medium of Streptomyces sp. AA0310. Lagunamycin has a significant inhibitory activity against rat 5-lipoxygenase with an IC50 value of 6.08 μM. Lagunamycin can effectively inhibit 5-lipoxygenase without causing lipid peroxidation, indicating that it has an effective inhibitory effect without causing side effects.

Molecular Weight

355.39

Formula

C19H21N3O4

CAS No.
SMILES

O=C1NC2=C(C(C(C(C2=O)=O)=[N+]=[N-])=O)C(/C(C)=C/[C@H](C)CC(C)C)=C1C

Structure Classification
Initial Source

Streptomyces sp.

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lagunamycin
Cat. No.:
HY-120721
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