2. Anti-infection Membrane Transporter/Ion Channel
  3. Antibiotic Bacterial Proton Pump
  4. TS 155-2

TS 155-2 (JBIR 100), an antimicrobial agent, is a Bafilomycin analogue and an antibiotic. TS 155-2 can be isolated from a culture of Streptomyces sp. TS 155-2 inhibits V-ATPase activity. V-ATPase is correlated with an increasing number of diseases such as osteopetrosis, male infertility and renal acidosis.

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TS 155-2 Chemical Structure

TS 155-2 Chemical Structure

CAS No. : 1314486-37-7

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TS 155-2 Related Antibodies

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Description

TS 155-2 (JBIR 100), an antimicrobial agent, is a Bafilomycin analogue and an antibiotic. TS 155-2 can be isolated from a culture of Streptomyces sp. TS 155-2 inhibits V-ATPase activity. V-ATPase is correlated with an increasing number of diseases such as osteopetrosis, male infertility and renal acidosis[1][2].

In Vitro

TS 155-2 shows cytotoxic effect against HeLa cells (IC50: 72.6 nM) at 48 h[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TS 155-2 Related Antibodies
Molecular Weight

704.89

Formula

C39H60O11
CAS No.
SMILES

O=C(O[C@@H]1C[C@@]([C@@H](C)[C@H](O)[C@@H]([C@H]([C@@H](OC)/C=C/C=C(C)/C[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C=C2\C)OC2=O)C)(O)O[C@H](C(C)C)[C@H]1C)/C=C/C(O)=O
Structure Classification
Initial Source

Streptomyces sp. IR027-SDHV6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TS 155-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TS 155-21314486-37-7JBIR 100JBIR100JBIR-100AntibioticBacterialProton PumpantimicrobialV-ATPaseInhibitorinhibitorinhibit

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