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Sulfoximine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106376B
    DL-Buthionine-(S,R)-sulfoximine hydrochloride
    Maximum Cited Publications
    16 Publications Verification

    Buthionine Sulfoximine hydrochloride; BSO hydrochloride

    		 Ferroptosis Cancer
    DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
    DL-Buthionine-(S,R)-sulfoximine hydrochloride
  • HY-106376
    DL-Buthionine-(S,R)-sulfoximine
    Maximum Cited Publications
    16 Publications Verification

    Buthionine Sulfoximine; BSO

    		 Ferroptosis Cancer
    DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
    DL-Buthionine-(S,R)-sulfoximine
  • HY-106376A
    L-Buthionine-(S,R)-sulfoximine
    5+ Cited Publications

    L-Buthionine Sulfoximine; L-BSO

    		 Ferroptosis Cancer
    L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
    L-Buthionine-(S,R)-sulfoximine
  • HY-106376C
    L-Buthionine-(S,R)-sulfoximine hydrochloride
    5+ Cited Publications

    L-Buthionine Sulfoximine hydrochloride; L-BSO hydrochloride

    		 Ferroptosis Metabolic Disease Cancer
    L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively .
    L-Buthionine-(S,R)-sulfoximine hydrochloride
  • HY-B1692
    L-Methionine-DL-sulfoximine
    2 Publications Verification

    MSX; MSO

    		 Glutaminase Neurological Disease
    L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .
    L-Methionine-DL-sulfoximine
  • HY-W338140
    Methionine sulfoximine

    2-Amino-4-(S-methylsulfonimidoyl)butanoic acid

    		 Others Neurological Disease
    Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase with convulsive effects. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine, which may provide important insights in neurobiological research. Methionine sulfoximine has also been used to study mechanisms related to epilepsy and its inhibitory potential .
    Methionine sulfoximine
  • HY-118504
    Sulfoxaflor

    		nAChR Neurological Disease
    Sulfoxaflor is a sulfoximine insecticide and is an agonist of nAChR1 and nAChR2 subtypes. Sulfoxaflor is used for the control of sap-feeding insects such as Myzus persicae, Aphis gossypii, Bemissia tabaci and Nilaparvata lugens .
    Sulfoxaflor
  • HY-19323A
    (S)-Ceralasertib
    1 Publications Verification

    (S)-AZD6738

    		 ATM/ATR Cancer
    (S)-Ceralasertib ((S)-AZD6738) is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2.578 nM . (S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. (S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition .
    (S)-Ceralasertib
  • HY-118504R
    Sulfoxaflor (Standard)

    		nAChR Neurological Disease
    Sulfoxaflor (Standard) is the analytical standard of Sulfoxaflor. This product is intended for research and analytical applications. Sulfoxaflor is a sulfoximine insecticide and is an agonist of nAChR1 and nAChR2 subtypes. Sulfoxaflor is used for the control of sap-feeding insects such as Myzus persicae, Aphis gossypii, Bemissia tabaci and Nilaparvata lugens .
    Sulfoxaflor (Standard)
  • HY-123815
    BRD5459

    		ROS Kinase Cancer
    BRD5459 is a ROS chemical probe. BRD5459 can increase ROS, a marker of oxidative stress in cells, without causing cell death .
    BRD5459

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