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Results for "

antianginal

" in MedChemExpress (MCE) Product Catalog:

53

Inhibitors & Agonists

1

Peptides

11

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0317A
    Amlodipine maleate
    5+ Cited Publications

    		 Calcium Channel Cardiovascular Disease Cancer
    Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer .
    Amlodipine maleate
  • HY-B0317
    Amlodipine
    5+ Cited Publications

    		 Calcium Channel Cardiovascular Disease Cancer
    Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer .
    Amlodipine
  • HY-B0317B
    Amlodipine besylate
    5+ Cited Publications

    Amlodipine benzenesulfonate

    		 Calcium Channel Cardiovascular Disease Cancer
    Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer .
    Amlodipine besylate
  • HY-164648
    Flosatidil

    SL 85-1016

    		 Calcium Channel Cardiovascular Disease
    Flosatidil (SL 85.1016) is an orally active Calcium Channel antagonist. Flosatidil has antianginal and antihypertensive properties .
    Flosatidil
  • HY-114638A
    Diproteverine hydrochloride

    BRL 40015 hydrochloride

    		 Calcium Channel Cardiovascular Disease
    Diproteverine hydrochloride is an oral activity calcium channel blocker. Diproteverine hydrochloride embryonic toxicity. Diproteverine hydrochloride also shows antianginal properties .
    Diproteverine hydrochloride
  • HY-117765
    RS-5773

    		Calcium Channel Cardiovascular Disease Neurological Disease
    RS-5773 is a calcium channel inhibitor and a diltiazem congener. RS-5773 has antianginal effect and does not cause excessive hypotension or depression of atrioventricular conduction .
    RS-5773
  • HY-114638
    Diproteverine

    BRL 40015

    		 Calcium Channel Cardiovascular Disease
    Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties .
    Diproteverine
  • HY-121215
    Chloracyzine

    		Histamine Receptor Cardiovascular Disease Neurological Disease
    Chloracyzine is an antianginal agent with spasmolytic properties and prevent or relieve spasms of the coronary vessels. Chloracyzine shows a moderate antihistaminic effect .
    Chloracyzine
  • HY-B0317C
    Amlodipine mesylate

    		Calcium Channel Cardiovascular Disease Cancer
    Amlodipine mesylate, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine mesylate can be used for the research of high blood pressure and cancer .
    Amlodipine mesylate
  • HY-B0317AS1
    Amlodipine-d9 maleate

    		Calcium Channel Isotope-Labeled Compounds Cardiovascular Disease
    Amlodipine-d9 maleate is deuterated labeled Amlodipine maleate (HY-B0317A). Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer .
    Amlodipine-d9 maleate
  • HY-B0317R
    Amlodipine (Standard)

    		Calcium Channel Cardiovascular Disease Cancer
    Amlodipine (Standard) is the analytical standard of Amlodipine. This product is intended for research and analytical applications. Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer .
    Amlodipine (Standard)
  • HY-B0317S1
    Amlodipine-d4

    		Isotope-Labeled Compounds Cancer
    Amlodipine-d4 is a deuterium labeled Amlodipine (HY-B0317). Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer .
    Amlodipine-d4
  • HY-16952A
    Bepridil hydrochloride hydrate
    5 Publications Verification

    (±)-Bepridil hydrochloride hydrate; Org 5730 hydrochloride hydrate

    		 Calcium Channel Cardiovascular Disease
    Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca + channel antagonist and Na +, K + channel inhibitor, with antianginal and type I antiarrhythmic effects. Bepridil hydrochloride hydrate also acts as a cardiac Na +/Ca2 + exchange (NCX1) inhibitor. Bepridil hydrochloride hydrate can be used for the research of cardiovascular disorders .
    Bepridil hydrochloride hydrate
  • HY-B0683
    Limaprost
    1 Publications Verification

    17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206

    		 PGE synthase Cardiovascular Disease Inflammation/Immunology
    Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .
    Limaprost
  • HY-B1264
    Celiprolol hydrochloride
    1 Publications Verification

    		 NO Synthase Adrenergic Receptor Cardiovascular Disease
    Celiprolol (REV 5320) is a potent, cardioselective and orally active β1-andrenoceptor r antagonist with partial β2 agonist activity, with Ki values of 0.14-8.3 μM. Celiprolol has antihypertensive and antianginal activity, and can be used for the research of cardiovascular disease such as high blood pressure .
    Celiprolol hydrochloride
  • HY-119873
    Celiprolol

    REV 5320

    		 NO Synthase Adrenergic Receptor Cardiovascular Disease
    Celiprolol (REV 5320) is a potent, cardioselective and orally active β1-andrenoceptor r antagonist with partial β2 agonist activity, with Ki values of 0.14-8.3 μM. Celiprolol has antihypertensive and antianginal activity, and can be used for the research of cardiovascular disease such as high blood pressure .
    Celiprolol
  • HY-101691
    Ecastolol

    		Adrenergic Receptor Cardiovascular Disease Endocrinology
    Ecastolol is a beta adrenergic receptor antagonist, with antianginal activities.
    Ecastolol
  • HY-103315
    Bepridil hydrochloride
    5 Publications Verification

    CERM 1978

    		 Calcium Channel Cardiovascular Disease
    Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.
    Bepridil hydrochloride
  • HY-133854
    L 8412

    		Others Cardiovascular Disease
    L 8412 is a potent anti-adrenergic agent and anti-anginal agent .
    L 8412
  • HY-B0284A
    Nifedipine hydrochloride

    		Others Cardiovascular Disease
    Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds .
    Nifedipine hydrochloride
  • HY-128696
    Amlodipine aspartic acid impurity

    Amlodipine aspartate

    		 Drug Metabolite Cardiovascular Disease
    Amlodipine aspartic acid impurity is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties.
    Amlodipine aspartic acid impurity
  • HY-U00151
    Dopropidil

    		Calcium Channel Cardiovascular Disease
    Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and anti-ischemic effects in several predictive animal models.
    Dopropidil
  • HY-U00151A
    Dopropidil hydrochloride

    		Calcium Channel Cardiovascular Disease
    Dopropidil hydrochloride is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and anti-ischemic effects in several predictive animal models.
    Dopropidil hydrochloride
  • HY-19115
    YM-430

    		Calcium Channel Adrenergic Receptor Cardiovascular Disease
    YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946)-induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris .
    YM-430
  • HY-B0317F
    Amlodipine hydrochloride

    		Calcium Channel Infection
    Amlodipine hydrochloride is a biologically active drug used to lower blood pressure and prevent chest pain. Amlodipine hydrochloride has shown synergistic effects with antimicrobial drugs in in vitro studies, especially against carbene peptide-resistant Acinetobacter baumannii. Amlodipine hydrochloride can be used in combination with other antibiotics to enhance the inhibitory effect against resistant bacteria. The use of amlodipine hydrochloride helps reduce the dosage requirements of the drug, reduce toxic effects, and delay the emergence of drug resistance .
    Amlodipine hydrochloride
  • HY-112075
    Lidoflazine

    		Potassium Channel Calcium Channel Cardiovascular Disease
    Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K + channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia .
    Lidoflazine
  • HY-135408
    Trimetazidine-N-oxide

    		Drug Metabolite Cardiovascular Disease Inflammation/Immunology
    Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.
    Trimetazidine-N-oxide
  • HY-126401
    Elgodipine

    IQB-875 free base

    		 Calcium Channel Cardiovascular Disease
    Elgodipine (IQB-875 free base) is an orally active dihydropyridine calcium antagonist and an antianginal compound. Elgodipine inhibits both T- and L-type calcium channels (IC50: 32 and 2.3 nM). Elgodipine lowers systemic vascular resistance and improves systolic cardiac function .
    Elgodipine
  • HY-B0162A
    Ivabradine hydrochloride
    2 Publications Verification

    		 HCN Channel Cardiovascular Disease Endocrinology Cancer
    Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity .
    Ivabradine hydrochloride
  • HY-B0162
    Ivabradine

    		HCN Channel Cardiovascular Disease Cancer
    Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity .
    Ivabradine
  • HY-B1517B
    Alprenolol benzoate

    		5-HT Receptor Cardiovascular Disease Cancer
    Alprenolol benzoate is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol benzoate is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent .
    Alprenolol benzoate
  • HY-B1517
    Alprenolol
    5+ Cited Publications

    (RS)-Alprenolol; dl-Alprenolol

    		 5-HT Receptor Cardiovascular Disease Cancer
    Alprenolol ((RS)-Alprenolol; dl-Alprenolol) is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent .
    Alprenolol
  • HY-B1517A
    Alprenolol hydrochloride
    5+ Cited Publications

    (RS)-Alprenolol hydrochloride; dl-Alprenolol hydrochloride

    		 5-HT Receptor Cardiovascular Disease Cancer
    Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent .
    Alprenolol hydrochloride
  • HY-B0280
    Ranolazine
    4 Publications Verification

    CVT 303; RS 43285-003

    		 Sodium Channel Calcium Channel Cardiovascular Disease Cancer
    Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) . Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor . Antianginal agent.
    Ranolazine
  • HY-B0317AS
    Amlodipine-d4 maleate

    		Isotope-Labeled Compounds Calcium Channel Cardiovascular Disease Cancer
    Amlodipine-d4 (maleate) is the deuterium labeled Amlodipine maleate. Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer[1][2][3].
    Amlodipine-d4 maleate
  • HY-129244
    Levamlodipine (gentisate)

    (S)-Amlodipine (gentisate); Levoamlodipine (gentisate)

    		 Calcium Channel Cardiovascular Disease
    Levamlodipine gentisate ((S)-Amlodipine gentisate) is a pharmacologically active amino ester with calcium channel blocker activity. Levamlodipine gentisate is used as an antihypertensive and antianginal compound. The enantiomeric purity of levamlodipine gentisate can be determined by a fast capillary electrophoresis method. The highest resolution of levamlodipine gentisate reached 9.8, indicating its potential application in compound analysis .
    Levamlodipine (gentisate)
  • HY-B0317S
    Amlodipine-1,1,2,2-d4 maleate

    		Isotope-Labeled Compounds Calcium Channel Cardiovascular Disease Cancer
    Amlodipine-1,1,2,2-d4 (maleate) is the deuterium labeled Amlodipine. Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer[1][2][3].
    Amlodipine-1,1,2,2-d4 maleate
  • HY-B0317BS
    Amlodipine-d4 besylate

    Amlodipine benzenesulfonate-d4 besylate

    		 Isotope-Labeled Compounds Calcium Channel Cardiovascular Disease Cancer
    Amlodipine-d4 (besylate) is the deuterium labeled Amlodipine besylate. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer[1][2][3].
    Amlodipine-d4 besylate
  • HY-B0162AR
    Ivabradine hydrochloride (Standard)

    		HCN Channel Cardiovascular Disease Endocrinology Cancer
    Ivabradine (hydrochloride) (Standard) is the analytical standard of Ivabradine (hydrochloride). This product is intended for research and analytical applications. Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity .
    Ivabradine hydrochloride (Standard)
  • HY-B0162S
    Ivabradine-d6

    		HCN Channel Cardiovascular Disease
    Ivabradine-d6 is the deuterium labeled Ivabradine[1]. Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity[2][3][4][5].
    Ivabradine-d6
  • HY-B0317BR
    Amlodipine besylate (Standard)

    Amlodipine benzenesulfonate (Standard)

    		 Calcium Channel Cardiovascular Disease Cancer
    Amlodipine (besylate) (Standard) is the analytical standard of Amlodipine (besylate). This product is intended for research and analytical applications. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer .
    Amlodipine besylate (Standard)
  • HY-B0968
    Trimetazidine dihydrochloride
    5 Publications Verification

    		 Autophagy Cardiovascular Disease
    Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
    Trimetazidine dihydrochloride
  • HY-B0280S2
    Ranolazine-d3

    		Sodium Channel Calcium Channel Cardiovascular Disease Cancer
    Ranolazine-d3 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.
    Ranolazine-d3
  • HY-B0280S1
    Ranolazine-d8

    		Isotope-Labeled Compounds Sodium Channel Calcium Channel Cardiovascular Disease Cancer
    Ranolazine-d8 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.
    Ranolazine-d8
  • HY-B0968A
    Trimetazidine
    5 Publications Verification

    		 Autophagy Cardiovascular Disease
    Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
    Trimetazidine
  • HY-B0280S
    Ranolazine-d5

    CVT 303-d5; RS 43285-003-d5

    		 Isotope-Labeled Compounds Sodium Channel Calcium Channel Cardiovascular Disease Cancer
    Ranolazine-d5 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.
    Ranolazine-d5
  • HY-B1517AR
    Alprenolol hydrochloride (Standard)

    (RS)-Alprenolol hydrochloride (Standard); dl-Alprenolol hydrochloride (Standard)

    		 5-HT Receptor Cancer
    Alprenolol (hydrochloride) (Standard) is the analytical standard of Alprenolol (hydrochloride). This product is intended for research and analytical applications. Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent .
    Alprenolol hydrochloride (Standard)
  • HY-B0280R
    Ranolazine (Standard)

    		Sodium Channel Calcium Channel Cardiovascular Disease Cancer
    Ranolazine (Standard) is the analytical standard of Ranolazine. This product is intended for research and analytical applications. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) . Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor . Antianginal agent.
    Ranolazine (Standard)
  • HY-B0968S
    Trimetazidine-d8 dihydrochloride

    		Autophagy Cardiovascular Disease
    Trimetazidine-d8 (dihydrochloride) is the deuterium labeled Trimetazidine dihydrochloride. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor[1][2][3][4].
    Trimetazidine-d8 dihydrochloride
  • HY-B0683S
    Limaprost-d3

    		PGE synthase Cardiovascular Disease Inflammation/Immunology
    Limaprost-d3 (17α,20-dimethyl-δ2-PGE1-d3) is the deuterium labeled Limaprost. Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research[1][2].
    Limaprost-d3

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