Search Result

Results for "

glycosylation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Akt (1) Amino Acid Derivatives (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (1) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (11) Complement System (1) Drug Metabolite (2) EGFR (1) Endogenous Metabolite (10) ERK (1) Estrogen Receptor/ERR (2) Fungal (4) Glucosylceramide Synthase (GCS) (1) HCV (2) HIV (1) HIV Integrase (2) Influenza Virus (3) JNK (1) Mitochondrial Metabolism (1) Monoamine Oxidase (1) Mucin (2) Notch (1) OGT (1) Oxidative Phosphorylation (1) PD-1/PD-L1 (1) PKC (2) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (17) Cardiovascular Disease (3) Infection (11) Inflammation/Immunology (6) Metabolic Disease (10) Neurological Disease (4)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (1) Alkynes (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W040294

Methyl α-D-glucoside Methyl α-D-glucopyranoside	Biochemical Assay Reagents	Others
Methyl α-D-glucoside (Methyl α-D-glucopyranoside) can be used for protein glycosylation modification. Methyl α-D-glucoside is a kind of biological materials or organic compounds that are widely used in life science research .

HY-113230B

Galactosylhydroxylysine hydrochloride	Endogenous Metabolite	Metabolic Disease
Galactosylhydroxylysine hydrochloride is a component of bone collagen produced by post-translational glycosylation of hydroxylysine. Galactosylhydroxylysine hydrochloride is released during bone resorption and has been shown to be elevated in metabolic bone loss .

HY-P0095

Acetyl tetrapeptide-5	Angiotensin-converting Enzyme (ACE)	Others
Acetyl tetrapeptide-5 inhibits *glycosylation* and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .

HY-138802

ML089 1 Publications Verification	Others	Metabolic Disease
ML089 is a potent, selective, and orally available phosphomannose isomerase (PMI) inhibitor with an IC₅₀ of 1.3 µM. ML089 can be used for the research of congenital disorder of glycosylation Ia .

HY-125732

Decarestrictine D	Others	Infection
Decarestrictine D exhibits inhibitory activity against cholesterol levels. Decarestrictine D is utilized as receptor for glycosylation reactions to synthesize novel hybrid antibiotics .

HY-113230

Galactosylhydroxylysine	Endogenous Metabolite	Metabolic Disease
Galactosylhydroxylysine is a component of bone collagen produced by post-translational glycosylation of hydroxylysine. Galactosylhydroxylysine is released during bone resorption and has been shown to be elevated in metabolic bone loss .

HY-116392E

D-threo-PDMP	Glucosylceramide Synthase (GCS)	Neurological Disease Metabolic Disease
D-threo-PDMP is a potent glucoceramide synthase (GCS) inhibitor, which reduces the glycosphingolipids on the cell surface by inhibiting glycosylation, reduces the total length of the axon plexus and the number of axon branch points, and inhibits neurite growth .

HY-157461

Glycation-IN-1	Others	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
Glycation-IN-1 (Compound 3) is an inhibitor of *glycosylation* reactions, which has a strong inhibitory effect on the synthesis of initial, intermediate, and final products of glycosylation reactions. Glycion-IN-1 can be used in the research of various chronic diseases, such as diabetes, immune inflammation, cardiovascular diseases and neurodegenerative diseases .

HY-164390

6′SLN Neu5Acα2-6Galβ1-4GlcNAc	Endogenous Metabolite	Infection Cancer
6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs .

HY-W415798

Ac4GalNAlk	Endogenous Metabolite	Others
Ac4GalNAlk is a weakly alkyne-labeled reagent for metabolic oligosaccharide engineering (MOE) that can be used to detect protein glycosylation. MOE reagents can be activated by cellular biosynthetic machinery into nucleotide sugars, which can be further traced through the introduction of glycoproteins in bioorthogonal chemistry. Ac4GalNAlk promotes nucleotide-sugar biosynthesis and increases bioorthogonal cell surface markers .

HY-W009783

1-Deoxymannojirimycin hydrochloride	HIV Influenza Virus	Infection
1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC₅₀ of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor and inhibits HIV‐1 strains. 1-Deoxymannojirimycin hydrochloride has antiviral activity .

HY-N1347

Robinetin 3,3',4',5',7-Pentahydroxyflavone	Fungal HIV Integrase Bacterial	Infection
Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation .

HY-N1347R

Robinetin (Standard)	Fungal HIV Integrase Bacterial	Infection
Robinetin (Standard) is the analytical standard of Robinetin. This product is intended for research and analytical applications. Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation .

HY-137042

Cyanine5 alkyne Alkyne-Cy5	Oxidative Phosphorylation Mitochondrial Metabolism	Cancer
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-E70292

N-Acetylgalactosaminyltransferase 11 GALNT11	Notch Endogenous Metabolite	Cardiovascular Disease
N-Acetylgalactosaminyltransferase 11 (GALNT11) is a glycosylation transferase capable of activating the Notch signal .

HY-156862

(+)-Chloroquine	Others	Others
(+)-Chloroquine is a aminoquinoline drug impairs in vitro the terminal glycosylation of angiotensin-converting enzyme 2 (ACE-2) .

HY-125849

Chrysin 7-O-beta-gentiobioside Chrysin 7-O-β-gentiobioside	Others	Cancer
Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside) is the glycosylation product of Chrysin .

HY-160109

Ac5GalNTGc	Mucin	Cancer
Ac5GalNTGc is a analog of hexosamine. Ac5GalNTGc inhibits mucin-type O-linked glycosylation biosynthesis .

HY-41588

2,3,4,6-Tetra-O-acetyl-D-glucopyranose, 96%	Biochemical Assay Reagents	Others
2,3,4,6-Tetra-O-acetyl-D-glucopyranose, 96% can be used in simulated glycosylation experiments.

HY-W039855A

1,2,3,4-Tetra-O-benzyl-β-D-glucopyranoside, 98%	Biochemical Assay Reagents	Others
1,2,3,4-Tetra-O-benzyl-β-D-glucopyranoside is a substrate for enzymatic glycosylation reactions and glycosyltransferase assays.

HY-W674039

6-Azido-6-deoxy-D-glucose, 95%	Biochemical Assay Reagents	Others
6-Azido-6-deoxy-D-glucose, 95% is used for visualizing protein-specific glycosylation in living cells.

HY-E70290

N-Acetylgalactosaminyltransferase 1 GALNT1	Endogenous Metabolite β-catenin Wnt	Cancer
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer can promote abnormal O-glycosylation of CD44, thereby activating the Wnt/β-catenin signaling pathway and regulating the malignant behavior of gastric cancer cells. Additionally, N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying the O-glycosylation of various glycoproteins, such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3 .

HY-E70104

α-Rhamnosidase α-L-Rhamnosidase	Others	Others
α-Rhamnosidase is a glycoside hydrolase. α-Rhamnosidase is able to finish the enzymatic de-glycosylation of many nature flavone glycosides .

HY-W661016

1-Azido-1-deoxy-β-D-galactopyranoside, 97% 1-Azido-1-deoxy-beta-D-galactopyranoside, 97%	Biochemical Assay Reagents	Others
1-Azido-1-deoxy-β-D-galactopyranoside, 97% is extensively used in research on glycosylation processes and enzyme mechanisms.

HY-W039939

2-Azido-2-deoxy-D-glucose, 98% 2-ADG, 98%	Biochemical Assay Reagents	Others
2-Azido-2-deoxy-D-glucose, 98% is a glycosylation inhibitor, which can be used to study the mechanisms of glycosylating enzymes.

HY-W378863

Methyl 2,3,5-tri-O-benzyl-β-D-ribofuranoside	Biochemical Assay Reagents
Methyl 2,3,5-tri-O-benzyl-β-D-ribofuranoside is a glycosylation reagent that can be used in the synthesis of oligosaccharides and polysaccharides .

HY-129389

Benzyl-α-GalNAc 1 Publications Verification	Others	Cancer
Benzyl-α-GalNAc is a potent *O-glycosylation* inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-FU (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation .

HY-W047324

4-Aminophenyl-α-D-mannopyranoside, 98% 4-Aminophenylmannoside, 98%	Biochemical Assay Reagents	Others
4-Aminophenyl-α-D-mannopyranoside, 98% is a synthetic glycoside primarily used as a molecular tool in biochemical research for studying glycosylation processes and enzyme-substrate interactions.

HY-W718137

6-Azido-6-deoxy-D-galactose，95%	Biochemical Assay Reagents	Others
6-Azido-6-deoxy-D-galactose, 95% can be used as a substrate in enzymology to study the activity and specificity of galactosyltransferases and other glycosylation enzymes.

HY-160109A

Ac5GalNTGc epimer	Mucin	Cancer
Ac5GalNTGc epimer is an analogue of hexosamine and the racemate of Ac5GalNTGc (HY-160109). Ac5GalNTGc inhibits mucin-type O-linked glycosylation biosynthesis .

HY-W008125

Acetobromo-α-D-glucuronic acid methyl ester, 98% Acetobromo-alpha-D-glucuronic acid methyl ester, 98%	Biochemical Assay Reagents	Others
Acetobromo-α-D-glucuronic acid methyl ester, 98% (Acetobromo-alpha-D-glucuronic acid methyl ester, 98%) can be used in glycobiology research and can undergo glycosylation reactions with suitable glycoside receptors.

HY-W013707

Cytidine-5'-triphosphate disodium dihydrate Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate	Endogenous Metabolite	Metabolic Disease
Cytidine-5'-triphosphate disodium dihydrate (5'-CTP disodium dihydrate) is a molecule of high energy, and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation .

HY-156905

6-Azido-N-acetylgalactosamine-UDP	Others	Cancer
6-Azido-N-acetylgalactosamine-UDP (compound 5) is an active sugar donor in the beta-1, 3-N-Acetylhexaminyltransferase (LgtA)-catalyzed glycosylation of lactose .

HY-N7603

Rubrofusarin triglucoside	Monoamine Oxidase	Neurological Disease
Rubrofusarin triglucoside is a glycoside compound isolated from Cassia obtusifolia Linn seeds. Rubrofusarin triglucoside inhibits human monoamine oxidase A (hMAO-A) with an IC₅₀ of 85.5 μM .

HY-P99322

Tesidolumab LFG316; Anti-Human C5 Recombinant Antibody	Complement System	Inflammation/Immunology
Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex .

HY-W039854

1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%	Biochemical Assay Reagents	Others
1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% (1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%) can be used in glycobiology research to study glycosylation mechanisms, glycosidic bond formation, and stereochemistry.

HY-E70295

N-Acetylgalactosaminyltransferase 14 GALNT14	Endogenous Metabolite	Cancer
N-Acetylgalactosaminyltransferase 14 (GALNT14) is a mucin-type glycosylating enzyme polypeptide that promotes the migration of ovarian cancer by modifying mucin 13 (MUC13). GALNT14 can regulate the O-glycosylation and stability of MUC13, thereby mediating the malignant behavior of ovarian cancer cells .

HY-129099

N-Desmethyltamoxifen	PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite	Cancer
N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation .

HY-129099A

N-Desmethyltamoxifen hydrochloride	PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite	Cancer
N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation .

HY-P4027

HCV-1 e2 Protein (554-569)	HCV	Infection
HCV-1 e2 Protein (554-569) is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) contains a putative n-glycosylation site, which was previously thought to influence the immune recognition of e2 .

HY-161424

ZJ-101	Others	Cancer
ZJ-101 is a structurally simplified analog derived from the marine natural product superstolide A. ZJ-101 exhibits potent antiproliferative activity. ZJ-101 can target and inhibit *O-glycosylation*, thereby modulating the endomembrane system. ZJ-101 can inhibit cell-cell adhesion .

HY-P4027A

HCV-1 e2 Protein (554-569) (TFA)	HCV	Infection
HCV-1 e2 Protein (554-569) TFA is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) TFA contains a putative N-glycosylation site, which was previously thought to influence the immune recognition of e2 .

HY-P99324

Tomuzotuximab Anti-Human EGFR Recombinant Antibody	EGFR Apoptosis	Cancer
Tomuzotuximab (Anti-Human EGFR Recombinant Antibody) is a fully human glycoengineered IgG1 monoclonal antibody against EGFR. Tomuzotuximab has anticancer effects .

HY-E70120

Phosphomannose isomerase	Fungal	Infection
Phosphomannose isomerase is the first enzyme involved in the biosynthesis pathway of GDP-Man. Phosphomannose isomerase catalyzes the conversion between fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P). Phosphomannose isomerase is important for cell wall synthesis and protein glycosylation. Phosphomannose isomerase is a potent antifungal target to curb the threats posed by A. flavus .

HY-A0098

Tunicamycin Maximum Cited Publications 92 Publications Verification	Bacterial Fungal Influenza Virus Antibiotic	Infection Inflammation/Immunology Cancer
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .

HY-135646

Eleutheroside B1	Influenza Virus	Infection Inflammation/Immunology
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC₅₀ value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .

HY-N7110

6-Hydroxyflavone	Akt ERK JNK	Neurological Disease Metabolic Disease Inflammation/Immunology
6-Hydroxyflavone is an orally effective flavonoid compound. 6-Hydroxyflavone can inhibit LPS (HY-D1056) -induced NO production and has anti-inflammatory effects. 6-Hydroxyflavone promotes osteoblast differentiation by activating AKT, ERK 1/2 and JNK signaling pathways. 6-Hydroxyflavone has an inhibitory effect on bovine hemoglobin (BHb) glycosylation. In addition, 6-Hydroxyflavone has anti-anxiety and kidney protective effects .

HY-124890

Thr101	Others	Metabolic Disease
Thr101 is an inhibitor (IC₅₀=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia) .

HY-P2232

Conalbumin Ovotransferrin	Others	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Conalbumin (Ovotransferrin), also known as ovotransferrin, is a monomeric glycoprotein consisting of 686 amino acids, encoded by the avian transferrin gene in the oviduct, and a prominent component of chicken egg white. Exhibiting a unique glycosylation pattern that differentiates it from serum transferrin, Conalbumin is a potent iron binder that plays a crucial role in iron transport to developing embryos. Additionally, it possesses a range of biological activities, including antimicrobial, antifungal, antiviral, anticancer, antioxidative, antihypertensive, and immunoregulatory properties, making it valuable in numerous applications such as infant formula ingredients, food additives, and agents for enhancing animal health.

HY-135785

OSMI-3	OGT Acyltransferase	Metabolic Disease
OSMI-3 (Compound 2b) is a potent, long-lasting, and cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-3 increases detained intron splicing in cells .

Cat. No.	Product Name	Type

HY-137042

Cyanine5 alkyne

Alkyne-Cy5

Fluorescent Dyes/Probes

Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Type

HY-W040294

Methyl α-D-glucoside Methyl α-D-glucopyranoside	Carbohydrates
Methyl α-D-glucoside (Methyl α-D-glucopyranoside) can be used for protein glycosylation modification. Methyl α-D-glucoside is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W008125

Acetobromo-α-D-glucuronic acid methyl ester, 98% Acetobromo-alpha-D-glucuronic acid methyl ester, 98%	Carbohydrates
Acetobromo-α-D-glucuronic acid methyl ester, 98% (Acetobromo-alpha-D-glucuronic acid methyl ester, 98%) can be used in glycobiology research and can undergo glycosylation reactions with suitable glycoside receptors.

HY-41588

2,3,4,6-Tetra-O-acetyl-D-glucopyranose, 96%	Carbohydrates
2,3,4,6-Tetra-O-acetyl-D-glucopyranose, 96% can be used in simulated glycosylation experiments.

HY-W039855A

1,2,3,4-Tetra-O-benzyl-β-D-glucopyranoside, 98%	Carbohydrates
1,2,3,4-Tetra-O-benzyl-β-D-glucopyranoside is a substrate for enzymatic glycosylation reactions and glycosyltransferase assays.

HY-W674039

6-Azido-6-deoxy-D-glucose, 95%	Indicators
6-Azido-6-deoxy-D-glucose, 95% is used for visualizing protein-specific glycosylation in living cells.

HY-W661016

1-Azido-1-deoxy-β-D-galactopyranoside, 97% 1-Azido-1-deoxy-beta-D-galactopyranoside, 97%	Carbohydrates
1-Azido-1-deoxy-β-D-galactopyranoside, 97% is extensively used in research on glycosylation processes and enzyme mechanisms.

HY-W039939

2-Azido-2-deoxy-D-glucose, 98% 2-ADG, 98%	Carbohydrates
2-Azido-2-deoxy-D-glucose, 98% is a glycosylation inhibitor, which can be used to study the mechanisms of glycosylating enzymes.

HY-W378863

Methyl 2,3,5-tri-O-benzyl-β-D-ribofuranoside	Carbohydrates
Methyl 2,3,5-tri-O-benzyl-β-D-ribofuranoside is a glycosylation reagent that can be used in the synthesis of oligosaccharides and polysaccharides .

HY-W047324

4-Aminophenyl-α-D-mannopyranoside, 98% 4-Aminophenylmannoside, 98%	Carbohydrates
4-Aminophenyl-α-D-mannopyranoside, 98% is a synthetic glycoside primarily used as a molecular tool in biochemical research for studying glycosylation processes and enzyme-substrate interactions.

HY-W718137

6-Azido-6-deoxy-D-galactose，95%	Carbohydrates
6-Azido-6-deoxy-D-galactose, 95% can be used as a substrate in enzymology to study the activity and specificity of galactosyltransferases and other glycosylation enzymes.

HY-W039854

1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%	Carbohydrates
1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% (1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%) can be used in glycobiology research to study glycosylation mechanisms, glycosidic bond formation, and stereochemistry.

HY-E70152

ST6 Sialyltransferase 4 EC:2.4.3.7; ST6GALNAC4; SIAT3-C	Enzyme Substrates
ST6 Sialyltransferase 4 (EC:2.4.3.7; ST6GALNAC4; SIAT3-C; SIAT3C; SIAT7-D; SIAT7D) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST6 Sialyltransferase 4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation. .

Cat. No.	Product Name	Target	Research Area

HY-P0095

Acetyl tetrapeptide-5	Angiotensin-converting Enzyme (ACE)	Others
Acetyl tetrapeptide-5 inhibits *glycosylation* and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .

HY-P4027

HCV-1 e2 Protein (554-569)	HCV	Infection
HCV-1 e2 Protein (554-569) is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) contains a putative n-glycosylation site, which was previously thought to influence the immune recognition of e2 .

HY-P4027A

HCV-1 e2 Protein (554-569) (TFA)	HCV	Infection
HCV-1 e2 Protein (554-569) TFA is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) TFA contains a putative N-glycosylation site, which was previously thought to influence the immune recognition of e2 .

HY-P3118

Bz-IEGR-pNA acetate	Peptides	Others
Bz-IEGR-pNA acetate is a trypsin substrate that can be hydrolyzed by prostate kinase release enzyme-related peptide KLKs .

HY-W072147

Fmoc-Ser-OMe Fmoc-L-Ser-OMe	Amino Acid Derivatives	Others
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .

Cat. No.	Product Name	Target	Research Area

HY-P99322

Tesidolumab LFG316; Anti-Human C5 Recombinant Antibody	Complement System	Inflammation/Immunology
Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex .

HY-P99324

Tomuzotuximab Anti-Human EGFR Recombinant Antibody	EGFR Apoptosis	Cancer
Tomuzotuximab (Anti-Human EGFR Recombinant Antibody) is a fully human glycoengineered IgG1 monoclonal antibody against EGFR. Tomuzotuximab has anticancer effects .

Species:	Human (10) Mouse (4) Cynomolgus (1)
Tag:	His (11) Tag Free (2) Myc (1) Fc (2)
Source:	HEK293 (5) P. pastoris (1) E. coli (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P700425

	MIF Protein, Human (HEK293, hFc) MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; phenylpyruvate tautomerase; glycosylation-inhibiting factor; EC 5.3.2.1; glycosylation-inhibiting factor; Phenylpyruvate tautomerase	Human	HEK293
	The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF Protein, Human (HEK293, hFc) is the recombinant human-derived MIF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of MIF Protein, Human (HEK293, hFc) is 114 a.a., with molecular weight of 41.3 kDa.

HY-P700517

	MIF Protein, Mouse (P. pastoris, His) MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; phenylpyruvate tautomerase; glycosylation-inhibiting factor; EC 5.3.2.1; glycosylation-inhibiting factor; Phenylpyruvate tautomerase	Mouse	P. pastoris
	The MIF protein is a pro-inflammatory cytokine that plays a crucial role in the innate immune response against bacterial pathogens.Its presence at sites of inflammation suggests its role as a mediator in the regulation of macrophage function during host defense.MIF Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived MIF protein, expressed by P.pastoris , with N-6*His labeled tag.

HY-P74425

	AGER Protein, Mouse (HEK293, His) Advanced glycosylation end product-specific receptor; Ager; Rage	Mouse	HEK293
	AGER proteins have multiple activities, including binding to S100 proteins, advanced glycation end products, and heparin. It is involved in cellular responses to amyloid, regulation of synaptic potentiation, and cytokine production. AGER Protein, Mouse (HEK293, His) is the recombinant mouse-derived AGER protein, expressed by HEK293 , with C-His labeled tag.

HY-P74604

	AGER Protein, Human (HEK293, hFc) Advanced glycosylation end product-specific receptor; Ager; Rage	Human	HEK293
	AGER proteins are cell surface pattern recognition receptors that expertly sense endogenous stress signals utilizing an extensive library of ligands, including advanced glycation end products, S100 proteins, high mobility Group Box 1 proteins/HMGB1, starch Like protein β/APP oligomers, nucleic acids, phospholipids, and glycosaminoglycans. AGER Protein, Human (HEK293, hFc) is the recombinant human-derived AGER protein, expressed by HEK293 , with C-hFc labeled tag. The total length of AGER Protein, Human (HEK293, hFc) is 321 a.a., with molecular weight of approximately 76.18 kDa.

HY-P700146AF

	Animal-Free AGER Protein, Human (His) Advanced glycosylation end product-specific receptor; Ager; RAGE	Human	E. coli
	AGER proteins are cell surface pattern recognition receptors that expertly sense endogenous stress signals utilizing an extensive library of ligands, including advanced glycation end products, S100 proteins, high mobility Group Box 1 proteins/HMGB1, starch Like protein β/APP oligomers, nucleic acids, phospholipids, and glycosaminoglycans. Animal-Free AGER Protein, Human (His) is the recombinant human-derived animal-FreeAGER protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free AGER Protein, Human (His) is 278 a.a., with molecular weight of ~30.94 kDa.

HY-P74605

	AGER Protein, Human (HEK293) Advanced glycosylation end product-specific receptor; Ager; Rage	Human	HEK293
	AGER proteins are cell surface pattern recognition receptors that expertly sense endogenous stress signals utilizing an extensive library of ligands, including advanced glycation end products, S100 proteins, high mobility Group Box 1 proteins/HMGB1, starch Like protein β/APP oligomers, nucleic acids, phospholipids, and glycosaminoglycans. AGER Protein, Human (HEK293) is the recombinant human-derived AGER protein, expressed by HEK293 , with tag free. The total length of AGER Protein, Human (HEK293) is 322 a.a., with molecular weight of 46-52 kDa.

HY-P700513

	MIF Protein, Human (N-His, C-Myc) MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; phenylpyruvate tautomerase; glycosylation-inhibiting factor; EC 5.3.2.1; glycosylation-inhibiting factor; Phenylpyruvate tautomerase	Human	E. coli
	The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF counteracts the anti-inflammatory effects of glucocorticoids. Although MIF exhibits tautomerase activity in vitro, its physiological substrates remain unknown, and the relevance of this activity to its cytokine function is unclear. MIF Protein, Human (N-His, C-Myc) is the recombinant human-derived MIF protein, expressed by E. coli, with C-Myc, N-10*His labeled tag. The total length of MIF Protein, Human (N-His, C-Myc) is 114 a.a., with molecular weight of 17.1 kDa.

HY-P701085

	AGER Protein, Cynomolgus (HEK293, His) Advanced glycosylation end-product specific receptor; AGER; RAGE; SCARJ1	Cynomolgus	HEK293
	AGER protein is a cell surface pattern recognition receptor that can sense endogenous stress signals from a variety of ligands, such as S100 protein, HMGB1, β-amyloid, etc. AGER Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived AGER protein, expressed by HEK293 , with C-His labeled tag. The total length of AGER Protein, Cynomolgus (HEK293, His) is 331 a.a., with molecular weight of 50-65 kDa.

HY-P701456

	ALG13 Protein, Human ALG13; Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; Asparagine-linked glycosylation 13 homolog; Glycosyltransferase 28 domain-containing protein 1; UDP-N-acetylglucosamine transferase subunit ALG13 homolog	Human	E. coli
	ALG13 protein is suggested to be a multifunctional enzyme with glycosyltransferase and deubiquitinase activities, playing a role in the second step of the dolichol-linked oligosaccharide pathway for protein N-glycosylation. This implies ALG13's involvement in vital cellular processes, bridging glycosylation and deubiquitination activities and highlighting its potential significance in regulating protein modifications and cellular pathways. ALG13 Protein, Human is the recombinant human-derived ALG13 protein, expressed by E. coli , with tag free. The total length of ALG13 Protein, Human is 152 a.a., .

HY-P701457

	ALG13 Protein, Human (His) ALG13; Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; Asparagine-linked glycosylation 13 homolog; Glycosyltransferase 28 domain-containing protein 1; UDP-N-acetylglucosamine transferase subunit ALG13 homolog	Human	E. coli
	ALG13 protein is suggested to be a multifunctional enzyme with glycosyltransferase and deubiquitinase activities, playing a role in the second step of the dolichol-linked oligosaccharide pathway for protein N-glycosylation. This implies ALG13's involvement in vital cellular processes, bridging glycosylation and deubiquitination activities and highlighting its potential significance in regulating protein modifications and cellular pathways. ALG13 Protein, Human (His) is the recombinant human-derived ALG13 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ALG13 Protein, Human (His) is 152 a.a., .

HY-P70288

	MIF Protein, Human (His) rHuMacrophage migration inhibitory factor/MIF, His; Macrophage migration inhibitory factor; MIF; MMIF; glycosylation-inhibiting factor; GLIF; L-dopachrome tautomerase; Phenylpyruvate tautomerase	Human	E. coli
	The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF counteracts the anti-inflammatory effects of glucocorticoids. Although MIF exhibits tautomerase activity in vitro, its physiological substrates remain unknown, and the relevance of this activity to its cytokine function is unclear. MIF Protein, Human (His) is the recombinant human-derived MIF protein, expressed by E. coli, with N-6*His labeled tag. The total length of MIF Protein, Human (His) is 115 a.a., with molecular weight of 10-14 kDa.

HY-P70288A

	MIF Protein, Human (N-His) rHuMacrophage migration inhibitory factor/MIF, His; Macrophage migration inhibitory factor; MIF; MMIF; glycosylation-inhibiting factor; GLIF; L-dopachrome tautomerase; Phenylpyruvate tautomerase	Human	E. coli
	The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF Protein, Human (N-His) is the recombinant human-derived MIF protein, expressed by E. coli , with N-6*His labeled tag. The total length of MIF Protein, Human (N-His) is 115 a.a., with molecular weight of approximately 11.67 kDa.

HY-P70288AF

	Animal-Free MIF Protein, Human (His) rHuMacrophage migration inhibitory factor/MIF, His; Macrophage migration inhibitory factor; MIF; MMIF; glycosylation-inhibiting factor; GLIF; L-dopachrome tautomerase; Phenylpyruvate tautomerase	Human	E. coli
	The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. Animal-Free MIF Protein, Human (His) is the recombinant human-derived animal-FreeMIF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free MIF Protein, Human (His) is 115 a.a., with molecular weight of ~13.28 kDa.

HY-P70341

	MIF Protein, Mouse (His) rMuMacrophage migration inhibitory factor/MIF, His; Macrophage migration inhibitory factor; Delayed early response protein 6; DER6; glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; Phenylpyruvate tautomerase;	Mouse	E. coli
	The MIF protein is a pro-inflammatory cytokine that plays a crucial role in the innate immune response against bacterial pathogens.Its presence at sites of inflammation suggests its role as a mediator in the regulation of macrophage function during host defense.MIF Protein, Mouse (His) is the recombinant mouse-derived MIF protein, expressed by E.coli , with C-6*His labeled tag.

HY-P70341AF

	Animal-Free MIF Protein, Mouse (His) rMuMacrophage migration inhibitory factor/MIF, His; Macrophage migration inhibitory factor; Delayed early response protein 6; DER6; glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; Phenylpyruvate tautomerase;	Mouse	E. coli
	The MIF protein is a pro-inflammatory cytokine that plays a crucial role in the innate immune response against bacterial pathogens.Its presence at sites of inflammation suggests its role as a mediator in the regulation of macrophage function during host defense.Animal-Free MIF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeMIF protein, expressed by E.coli , with C-His labeled tag.

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HY-P81087

	AGEs Antibody advanced glycosylation end products; AGE.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat,
	AGEs Antibody is an unconjugated, rabbit-derived, anti-AGEs polyclonal antibody. AGEs Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, background without labeling.

HY-P82167

	MIF Antibody (YA1912) MIF; GLIF; MMIF; Macrophage migration inhibitory factor; MIF; glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; Phenylpyruvate tautomerase	WB, IP, FC	Human, Mouse, Rat
	MIF Antibody (YA1912) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1912), targeting MIF, with a predicted molecular weight of 12 kDa (observed band size: 13 kDa). MIF Antibody (YA1912) can be used for WB, IP, FC experiment in human, mouse, rat background.

HY-P81086

	RAGE Antibody Advanced glycosylation end product specific receptor; Advanced glycosylation end product-specific receptor; AGER; EC 2.7.11.22; LE 9211 A antigen; LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; Receptor for advanced glycation endproducts; Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat,
	RAGE Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-RAGE polyclonal antibody. RAGE Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, background without labeling.

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HY-137042

Cyanine5 alkyne Alkyne-Cy5		Alkynes Labeling and Fluorescence Imaging
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W415798

Ac4GalNAlk		Alkynes
Ac4GalNAlk is a weakly alkyne-labeled reagent for metabolic oligosaccharide engineering (MOE) that can be used to detect protein glycosylation. MOE reagents can be activated by cellular biosynthetic machinery into nucleotide sugars, which can be further traced through the introduction of glycoproteins in bioorthogonal chemistry. Ac4GalNAlk promotes nucleotide-sugar biosynthesis and increases bioorthogonal cell surface markers .

HY-W674039

6-Azido-6-deoxy-D-glucose, 95%		Azide
6-Azido-6-deoxy-D-glucose, 95% is used for visualizing protein-specific glycosylation in living cells.

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