1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. Acetyl tetrapeptide-5

Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Acetyl tetrapeptide-5 Chemical Structure

Acetyl tetrapeptide-5 Chemical Structure

CAS No. : 820959-17-9

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50 mg USD 70 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care[1][2][3].

IC50 & Target

ACE-1[1]

In Vitro

Acetyl tetrapeptide-5 (100 μg/mL) inhibits angiotensin-converting enzyme 1 (ACE-1) activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

492.49

Formula

C20H28N8O7

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ac-β-{Ala}-His-Ser-His-OH

Sequence Shortening

Ac-β-{Ala}-HSH

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (50.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0305 mL 10.1525 mL 20.3050 mL
5 mM 0.4061 mL 2.0305 mL 4.0610 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0305 mL 10.1525 mL 20.3050 mL 50.7625 mL
5 mM 0.4061 mL 2.0305 mL 4.0610 mL 10.1525 mL
10 mM 0.2030 mL 1.0152 mL 2.0305 mL 5.0762 mL
15 mM 0.1354 mL 0.6768 mL 1.3537 mL 3.3842 mL
20 mM 0.1015 mL 0.5076 mL 1.0152 mL 2.5381 mL
25 mM 0.0812 mL 0.4061 mL 0.8122 mL 2.0305 mL
30 mM 0.0677 mL 0.3384 mL 0.6768 mL 1.6921 mL
40 mM 0.0508 mL 0.2538 mL 0.5076 mL 1.2691 mL
50 mM 0.0406 mL 0.2030 mL 0.4061 mL 1.0152 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Acetyl tetrapeptide-5
Cat. No.:
HY-P0095
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