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Results for "

hyperthyroidism

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cytochrome P450 (1) Isotope-Labeled Compounds (1) p38 MAPK (2) TNF Receptor (1) VD/VDR (1)
By Research Areas:	Endocrinology (9) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W069177

Benzylthiouracil 6-Benzyl-2-thiouracil	Others	Others
Benzylthiouracil is an active pharmaceutical ingredient against hyperthyroidism .

HY-B0208S

Methimazole-d3	Isotope-Labeled Compounds	Endocrinology
Methimazole-d₃ is a deuterium labeled Methimazole. Methimazole is an antithyroid agent used for the treatment of the hyperthyroidism in humans and animals[1].

HY-P99670

Iscalimab CFZ-533; OM11-62MF	TNF Receptor	Metabolic Disease Inflammation/Immunology
Iscalimab (CFZ-533) is a non-depleting IGg1 monoclonal antibody targeting CD40 (K_D: 0.3 nM). Iscalimab can be used for research of Graves' hyperthyroidism and autoimmune diseases .

HY-B0558

Carbimazole	p38 MAPK	Neurological Disease Endocrinology
Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .

HY-107916

Thyrotropin 1 Publications Verification TSH; Pretiron	Others	Metabolic Disease Endocrinology
Thyrotropin is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .

HY-B0208

Methimazole 1 Publications Verification Thiamazole	Others	Endocrinology
Methimazole is an antithyroid compound widely used for the research of hyperthyroidism. Methimazole has potent hepatotoxicity .

HY-B0346

Propylthiouracil 1 Publications Verification 6-n-Propylthiouracil; 6-Propyl-2-thiouracil; PTU	Others	Endocrinology
Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .

HY-B0208R

Methimazole (Standard)	Others	Endocrinology
Methimazole (Standard) is the analytical standard of Methimazole. This product is intended for research and analytical applications. Methimazole is an antithyroid compound widely used for the research of hyperthyroidism. Methimazole has potent hepatotoxicity .

HY-B0346R

Propylthiouracil (Standard)	Others	Endocrinology
Propylthiouracil (Standard) is the analytical standard of Propylthiouracil. This product is intended for research and analytical applications. Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .

HY-B0558R

Carbimazole (Standard)	p38 MAPK	Neurological Disease Endocrinology
Carbimazole (Standard) is the analytical standard of Carbimazole. This product is intended for research and analytical applications. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .

HY-14863

Lunacalcipol CTA-018	VD/VDR Cytochrome P450	Others Endocrinology
Lunacalcipol (CTA-018), as a vitamin D analogue, has a dual role in the pathogenesis of Chronic Kidney Disease (CKD), as an agonist of vitamin D receptor and an antagonist of cytochrome P450 enzyme 24-hydroxylase. Lunacalcipol binds to VDR and regulates transcriptional activity of VDR by influencing ligand binding affinity, ligand-dependent coactivator recruitment or inhibitory factor dissociation, efficiency of ligand entry into target cells, tissue specificity and different metabolism of ligand. Lunacalcipol can be used in the study of CKD, especially Secondary Hyperparathyroidism (sHPT) .

Cat. No.	Product Name

HY-L182

Fatty Acids Compound Library	292 compounds
Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases. MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Fatty Acids Compound Library

292 compounds

Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases.

MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Cat. No.	Product Name	Target	Research Area