1. Others
  2. Isotope-Labeled Compounds
  3. Methimazole-d3

Methimazole-d3 is a deuterium labeled Methimazole. Methimazole is an antithyroid agent used for the treatment of the hyperthyroidism in humans and animals[1].

For research use only. We do not sell to patients.

Methimazole-d<sub>3</sub> Chemical Structure

Methimazole-d3 Chemical Structure

CAS No. : 1160932-07-9

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500 μg USD 110 In-stock
1 mg USD 190 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Methimazole-d3:

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Description

Methimazole-d3 is a deuterium labeled Methimazole. Methimazole is an antithyroid agent used for the treatment of the hyperthyroidism in humans and animals[1].

Molecular Weight

117.19

Formula

C4H3D3N2S

CAS No.
Unlabeled CAS

60-56-0

Appearance

Solid

Color

White to off-white

SMILES

S=C1NC=CN1C([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (853.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 100 mg/mL (853.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (426.66 mM)

H2O : ≥ 50 mg/mL (426.66 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.5332 mL 42.6658 mL 85.3315 mL
5 mM 1.7066 mL 8.5332 mL 17.0663 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / DMSO / DMSO 1 mM 8.5332 mL 42.6658 mL 85.3315 mL 213.3288 mL
5 mM 1.7066 mL 8.5332 mL 17.0663 mL 42.6658 mL
10 mM 0.8533 mL 4.2666 mL 8.5332 mL 21.3329 mL
15 mM 0.5689 mL 2.8444 mL 5.6888 mL 14.2219 mL
20 mM 0.4267 mL 2.1333 mL 4.2666 mL 10.6664 mL
25 mM 0.3413 mL 1.7066 mL 3.4133 mL 8.5332 mL
30 mM 0.2844 mL 1.4222 mL 2.8444 mL 7.1110 mL
40 mM 0.2133 mL 1.0666 mL 2.1333 mL 5.3332 mL
50 mM 0.1707 mL 0.8533 mL 1.7066 mL 4.2666 mL
60 mM 0.1422 mL 0.7111 mL 1.4222 mL 3.5555 mL
80 mM 0.1067 mL 0.5333 mL 1.0666 mL 2.6666 mL
100 mM 0.0853 mL 0.4267 mL 0.8533 mL 2.1333 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Methimazole-d3
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HY-B0208S
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