2. Immunology/Inflammation
  3. AP-1
  4. 12(S)-HPETE

12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE induces the expression of c-Fos and c-Jun protein and increases activating protein 1 (AP-1) activity in vascular smooth muscle cells.12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension.

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12(S)-HPETE Chemical Structure

12(S)-HPETE Chemical Structure

CAS No. : 71774-10-2

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50 μg Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
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Based on 1 publication(s) in Google Scholar

12(S)-HPETE Related Antibodies

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c-Fos c-Jun

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Description

12(S)-HPETE is a 12-hydroxyeicosatetraenoic acid. 12(S)-HPETE has the function of regulating vascular tone. 12(S)-HPETE induces the expression of c-Fos and c-Jun protein and increases activating protein 1 (AP-1) activity in vascular smooth muscle cells.12(S)-HPETE may play a physiological role in vasomotor regulation through endothelium itself and crosstalk between blood cells and endothelium. 12(S)-HPETE can be used in the study of cerebrovascular tension[1][2].

Molecular Weight

336.47

Formula

C20H32O4
CAS No.
SMILES

CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(O)=O
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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12(S)-HPETE Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

12(S)-HPETE71774-10-2AP-1Activator Protein 112-lipoxygenasearachidonic acidendothelium-dependent contractionbasilar arteryInhibitorinhibitorinhibit

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