2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-23498
    Benzo[k]fluoranthene
    Benzo[k]fluoranthene is a polycyclic aromatic hydrocarbon (PAH) that is carcinogenic and genotoxic.
    Benzo[k]fluoranthene
  • HY-101981S2
    Uridine 5'-monophosphate-d11 dilithium
    Uridine 5'-monophosphate-d11 (5'-?Uridylic acid-d11) dilithium is deuterium labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
    Uridine 5'-monophosphate-d<sub>11</sub> dilithium
  • HY-117313
    Fumitremorgin B
    Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL.
    Fumitremorgin B
  • HY-P2999
    Endo-β-N-acetylglucosaminidase
    Endo-β-N-acetylglucosaminidase (ENGase) is cytosolic deglycosylating enzyme that hydrolyzes the N-linked oligosaccharides. Endo-β-N-acetylglucosaminidase can be used for glycan analysis on glycoproteins and preparation of precursors for glycosylated compounds, is often used in biochemical studies.
    Endo-β-N-acetylglucosaminidase
  • HY-19312R
    3-Methyladenine (Standard)
    3-Methyladenine (Standard) is the analytical standard of 3-Methyladenine. This product is intended for research and analytical applications. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
    3-Methyladenine (Standard)
  • HY-N1380S4
    Guaiacol-d4-1
    Guaiacol-d4-1 is the deuterium labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].
    Guaiacol-d<sub>4</sub>-1
  • HY-154921A
    Lactosylceramide (porcine RBC)
    Lactosylceramide (LacCer) (porcine RBC) is an endogenous bioactive sphingolipid. Lactosylceramide (porcine RBC) plays a pivotal role in mediating innate immune functions.
    Lactosylceramide (porcine RBC)
  • HY-Y0337S7
    L-Cysteine-d3,15N
    L-Cysteine-d3,15N is the deuterium and 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
    L-Cysteine-d<sub>3</sub>,<sup>15</sup>N
  • HY-W012499R
    N-Acetyl-L-methionine (Standard)
    N-Acetyl-L-methionine (Standard) is the analytical standard of N-Acetyl-L-methionine. This product is intended for research and analytical applications. N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development.
    N-Acetyl-L-methionine (Standard)
  • HY-N0131S1
    Stigmasterol-d5-1
    Stigmasterol-d5-1 is deuterium labeled Stigmasterol. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases[1].
    Stigmasterol-d<sub>5</sub>-1
  • HY-W006057AS13
    Sodium 3-methyl-2-oxobutanoate-13C4,d3
    Sodium 3-methyl-2-oxobutanoate-13C4,d3 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
    Sodium 3-methyl-2-oxobutanoate-<sup>13</sup>C<sub>4</sub>,d<sub>3</sub>
  • HY-13715BR
    Norepinephrine bitartrate monohydrate (Standard)
    Norepinephrine (bitartrate monohydrate) (Standard) is the analytical standard of Norepinephrine (bitartrate monohydrate). This product is intended for research and analytical applications. Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors.
    Norepinephrine bitartrate monohydrate (Standard)
  • HY-130053
    Nafenopin
    Nafenopin (SU-13-437) is a peroxidase proliferator with liver tumor promoting activity. Nafenopin is also used as an anti-hyperlipoproteinemia compound. Nafenopin is able to induce oxidative stress in vivo, showing its effects on the liver. The mechanism of action of nafenopin has differentiated features compared to other non-genotoxic carcinogens.
    Nafenopin
  • HY-W040094
    Cellobiosan
    Cellobiosan is an anhydrosugar, which is produced from burning of biomass.
    Cellobiosan
  • HY-B1227S1
    Carprofen-13C,d3
    Carprofen-13C,d3 is the deuterium and 13C labeled Carprofen[1]. Carprofen is a nonsteroid anti-inflammatory agent, acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 μM, 22.3 μM and 78.6 μM for COX-2, COX-1 and FAAH, respectively[2][3][4].
    Carprofen-<sup>13</sup>C,d<sub>3</sub>
  • HY-114293R
    Acetyl coenzyme A (Standard)
    Acetyl coenzyme A (Standard) is the analytical standard of Acetyl coenzyme A. This product is intended for research and analytical applications. Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis[4].
    Acetyl coenzyme A (Standard)
  • HY-N0181R
    Ergosterol (Standard)
    Ergosterol (Standard) is the analytical standard of Ergosterol. This product is intended for research and analytical applications. Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
    Ergosterol (Standard)
  • HY-161103
    Angeloyl-CoA
    Angeloyl-CoA is a CoA-activated form of angelic acid and has anticancer activity. Angeloyl-CoA can be produced based on yeast.
    Angeloyl-CoA
  • HY-N0650R
    L-Serine (Standard)
    L-Serine (Standard) is the analytical standard of L-Serine. This product is intended for research and analytical applications. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine (Standard)
  • HY-121765R
    Dacisteine (Standard)
    Dacisteine (Standard) is the analytical standard of Dacisteine. This product is intended for research and analytical applications. Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation.
    Dacisteine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity