2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Aminooxy-amido-PEG4-propargyl

Aminooxy-amido-PEG4-propargyl 

Cat. No.: HY-133435 Purity: ≥97.0%
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Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Aminooxy-amido-PEG4-propargyl Chemical Structure

Aminooxy-amido-PEG4-propargyl Chemical Structure

CAS No. : 2253965-03-4

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Based on 1 publication(s) in Google Scholar

Aminooxy-amido-PEG4-propargyl Related Antibodies

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Description

Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Non-cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aminooxy-amido-PEG4-propargyl Related Antibodies
Molecular Weight

304.34

Formula

C13H24N2O6
CAS No.
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

NOCC(NCCOCCOCCOCCOCC#C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Aminooxy-amido-PEG4-propargyl Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aminooxy-amido-PEG4-propargyl2253965-03-4ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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