2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. BDZ-P7

BDZ-P7 inhibits AMPA receptor GluA2, GluA1/2, GluA2/3, and GluA1 subunit with IC50s of 3.03 μM, 3.14 μM, 3.19 μM, 3.2 μM. BDZ-P7 has neuroprotective effect and reinstates locomotor abilities in a mouse model of Parkinson’s disease.

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BDZ-P7 Chemical Structure

BDZ-P7 Chemical Structure

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BDZ-P7 Related Antibodies

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

BDZ-P7 inhibits AMPA receptor GluA2, GluA1/2, GluA2/3, and GluA1 subunit with IC50s of 3.03 μM, 3.14 μM, 3.19 μM, 3.2 μM. BDZ-P7 has neuroprotective effect and reinstates locomotor abilities in a mouse model of Parkinson’s disease[1].

Molecular Weight

377.82

Formula

C19H20ClNO5
SMILES

CC(C(NC1=C(OC)C=C(Cl)C(OC)=C1)=O)CC2=CC(OCO3)=C3C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BDZ-P7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BDZ-P7iGluRIonotropic glutamate receptorsParkinson’sPDInhibitorinhibitorinhibit

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