Methionyl-tRNA formyltransferase, mitochondrial

Definition:

Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.

References:

[1]. Elena J Tucker, et al. Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation. Cell Metab. 2011 Sep 7;14(3):428-34. [Content Brief]

[2]. Akesh Sinha, et al. Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferase. J Biol Chem. 2014 Nov 21;289(47):32729-41. [Content Brief]

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