Pleckstrin homology-like domain family A member 1

Definition:

Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.

References:

[1]. T Hinz, et al. Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product. Cell Signal. 2001 May;13(5):345-52. [Content Brief]

[2]. Gazi S Hossain, et al. TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia. J Biol Chem. 2003 Aug 8;278(32):30317-27. [Content Brief]

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