Crustacean cardioactive peptide，free acid

Name: Crustacean cardioactive peptide，free acid
Brand: MedChemExpress
SKU: HY-P0303
Rating: 4.5 (1 reviews)

Cat. No.: HY-P0303 Purity: 99.44%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Crustacean cardioactive peptide，free acid Chemical Structure

CAS No. : 309247-84-5

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Ultrabithorax and Abdominal-A are not necessary for specification of the CCAP-interneurons, but are absolutely required to prevent the death by apoptosis of the CCAP-efferent neurons^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

CCAP, FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates, increase hemolymph flow velocity in the antennal space^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

959.10

Formula

C₄₂H₅₈N₁₀O₁₂S₂

CAS No.

309247-84-5

Appearance

Solid

Color

White to off-white

Sequence

Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys

Sequence Shortening

PFCNAFTGC

Structure Classification

Others

Initial Source

Animals

Acyrthosiphon pisum

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Purity & Documentation

Purity: 99.44%

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Data Sheet (259 KB) SDS (312 KB)

COA (308 KB) RP-HPLC (257 KB) LCMS (89 KB) Elemental Analysis Report (106 KB)

Handling Instructions (2659 KB)

References

[1]. Suggs JM, et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219(Pt 15):2388-95. [Content Brief]

[2]. Moris-Sanz M, et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4(9):1132-42. [Content Brief]