cIAP1 Ligand-Linker Conjugates 11 (Synonyms: E3 ligase Ligand-Linker Conjugates 33)

Cat. No.: HY-128812: FAQs
Data Sheet Handling Instructions

Molarity Calculator

cIAP1 Ligand-Linker Conjugates 11 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 can be used to design SNIPERs.

For research use only. We do not sell to patients.

cIAP1 Ligand-Linker Conjugates 11 Chemical Structure

CAS No. : 1239943-19-1

Size		Stock
1 g		Get quote	Estimated Time of Arrival: December 31
2 g		Get quote	Estimated Time of Arrival: December 31

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of cIAP1 Ligand-Linker Conjugates 11:

cIAP1 Ligand-Linker Conjugates 11 Hydrochloride Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

View All Isoforms

von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

Biological Activity
Purity & Documentation
References
Customer Review

Description

cIAP1 Ligand-Linker Conjugates 11 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 can be used to design SNIPERs^[1].

IC₅₀ & Target

cIAP1

Molecular Weight

617.73

Formula

C₃₅H₄₃N₃O₇

CAS No.

1239943-19-1

SMILES

NCCOCCOC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC1=CC=CC=C1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Itoh Y, et al. Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. J Am Chem Soc. 2010 Apr 28;132(16):5820-6. [Content Brief]

cIAP1 Ligand-Linker Conjugates 11 Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cIAP1 Ligand-Linker Conjugates 111239943-19-1E3 ligase Ligand-Linker Conjugates 33E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks