2. Oligonucleotides
  3. Antisense Oligonucleotides
  4. Eteplirsen sodium

Eteplirsen sodium  (Synonyms: AVI 4658 sodium)

Cat. No.: HY-108753A Purity: 90.43%
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Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. Eteplirsen (AVI 4658) sodium promotes exon 51 skipping in Duchenne muscular dystrophy patients and can be used in Duchenne muscular dystrophy research.

For research use only. We do not sell to patients.

RNA, [P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G), 5'-[P-[4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]carbonyl]-1-piperazinyl]-N,N-dimethylphosphonamidate], sodium salt

Eteplirsen sodium Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Eteplirsen sodium Related Antibodies

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Description

Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. Eteplirsen (AVI 4658) sodium promotes exon 51 skipping in Duchenne muscular dystrophy patients and can be used in Duchenne muscular dystrophy research[1].

Molecular Weight

10965.17

Formula

C364H539N177Na30O122P30
Appearance

Solid

Color

White to off-white

SMILES

[Eteplirsen (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Purity & Documentation
References
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Eteplirsen sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EteplirsenAVI 4658AVI4658AVI-4658OthersantisenseoligonucleotideDuchennemusculardystrophyDMDInhibitorinhibitorinhibit

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