1. Neuronal Signaling
  2. Amyloid-β
  3. FSB

FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm).

For research use only. We do not sell to patients.

FSB Chemical Structure

FSB Chemical Structure

CAS No. : 760988-03-2

Size Price Stock Quantity
1 mg USD 330 In-stock
5 mg USD 833 In-stock
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50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm)[1][2].

Molecular Weight

420.39

Formula

C24H17FO6

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC1=CC=C(/C=C/C2=CC=C(C(F)=C2)/C=C/C3=CC=C(C(C(O)=O)=C3)O)C=C1C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (475.75 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3787 mL 11.8937 mL 23.7874 mL
5 mM 0.4757 mL 2.3787 mL 4.7575 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3787 mL 11.8937 mL 23.7874 mL 59.4686 mL
5 mM 0.4757 mL 2.3787 mL 4.7575 mL 11.8937 mL
10 mM 0.2379 mL 1.1894 mL 2.3787 mL 5.9469 mL
15 mM 0.1586 mL 0.7929 mL 1.5858 mL 3.9646 mL
20 mM 0.1189 mL 0.5947 mL 1.1894 mL 2.9734 mL
25 mM 0.0951 mL 0.4757 mL 0.9515 mL 2.3787 mL
30 mM 0.0793 mL 0.3965 mL 0.7929 mL 1.9823 mL
40 mM 0.0595 mL 0.2973 mL 0.5947 mL 1.4867 mL
50 mM 0.0476 mL 0.2379 mL 0.4757 mL 1.1894 mL
60 mM 0.0396 mL 0.1982 mL 0.3965 mL 0.9911 mL
80 mM 0.0297 mL 0.1487 mL 0.2973 mL 0.7434 mL
100 mM 0.0238 mL 0.1189 mL 0.2379 mL 0.5947 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FSB
Cat. No.:
HY-D1494
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