2. Gene
  3. MIGA1 - mitoguardin 1 Gene

MIGA1 - mitoguardin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FAM73A

Gene ID: 374986 | Gene type: protein coding

About MIGA1

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:77,779,649-77,879,540 (from NCBI)

This gene has 9 transcripts (splice variants), 202 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 8.8), thyroid (RPKM 7.5) and 25 other tissues.

Summary

Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Located in mitochondrion. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MIGA1 Products(16)

mRNA Protein Name
NM_001270384.2 NP_001257313.1 mitoguardin 1 isoform 2
NM_001363583.1 NP_001350512.1 mitoguardin 1 isoform 3
NM_001363584.1 NP_001350513.1 mitoguardin 1 isoform 3
NM_001363586.1 NP_001350515.1 mitoguardin 1 isoform 3
NM_001394566.1 NP_001381495.1 mitoguardin 1 isoform 4
NM_001394567.1 NP_001381496.1 mitoguardin 1 isoform 5
NM_001394568.1 NP_001381497.1 mitoguardin 1 isoform 5
NM_001394569.1 NP_001381498.1 mitoguardin 1 isoform 5
NM_001394570.1 NP_001381499.1 mitoguardin 1 isoform 5
NM_001394571.1 NP_001381500.1 mitoguardin 1 isoform 3
NM_001394572.1 NP_001381501.1 mitoguardin 1 isoform 6
NM_001394573.1 NP_001381502.1 mitoguardin 1 isoform 7
NM_001394574.1 NP_001381503.1 mitoguardin 1 isoform 8
NM_001394575.1 NP_001381504.1 mitoguardin 1 isoform 9
NM_001394576.1 NP_001381505.1 mitoguardin 1 isoform 9
NM_198549.4 NP_940951.1 mitoguardin 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26711011 GOA
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
26711011 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
26711011 GOA
Biological Process GO Annotation Evidence Reference Source
involved in mitochondrial fusion IDA
IDA: Inferred from direct assay
26711011 GOA
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
26711011 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MIGA1 Protein Structure

Miga

Miga: Mitoguardin (59 - 603)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 632 a.a.
Protein Preferred Names Protein Names

mitoguardin 1

family with sequence similarity 73, member A

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08446 MIGA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MIGA1 VGNC VGNC:43232
Bos taurus MIGA1 VGNC VGNC:31473
Macaca mulatta MIGA1 VGNC VGNC:74819
Mus musculus MIGA1 MGD MGI:1924567
Felis catus MIGA1 VGNC VGNC:63504
Rattus norvegicus MIGA1 RGD RGD:1559958