2. Gene
  3. DNAH7 - dynein axonemal heavy chain 7 Gene

DNAH7 - dynein axonemal heavy chain 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 56171 | Gene type: protein coding

About DNAH7

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:195,737,703-196,068,837 (from NCBI)

This gene has 8 transcripts (splice variants), 238 orthologues and 15 paralogues. Biased expression in testis (RPKM 2.6), thyroid (RPKM 0.9) and 7 other tissues.

Summary

DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]

DNAH7 Products(1)

mRNA Protein Name
NM_018897.3 NP_061720.2 dynein axonemal heavy chain 7

DNAH7 Protein Structure

DHC_N2

DHC_N2: Dynein heavy chain, N-terminal region 2 (756 - 1166)

AAA_6

AAA_6: Hydrolytic ATP binding site of dynein motor region D1 (1290 - 1517)

AAA_7

AAA_7: P-loop containing dynein motor region D3 (1942 - 2211)

AAA_8

AAA_8: P-loop containing dynein motor region D4 (2304 - 2574)

MT

MT: Microtubule-binding stalk of dynein motor (2587 - 2933)

AAA_9

AAA_9: ATP-binding dynein motor region D5 (2958 - 3183)

Dynein_heavy

Dynein_heavy: Dynein heavy chain and region D6 of dynein motor (3319 - 4021)

  • 0
  • 700
  • 1400
  • 2100
  • 2800
  • 3500
  • 4024 a.a.
Protein Preferred Names Protein Names

dynein axonemal heavy chain 7

axonemal beta dynein heavy chain 7

Related Diseases

Diseases Alias
Basal Ganglia Disease

Basal Ganglia Diseases

Basal Ganglia Disorders

Abnormality Of The Basal Ganglia
Situs Inversus

Situs Inversus Viscerum

Laterality Sequence

Complete Transposition

Siv
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
Ciliary Dyskinesia, Primary, 36, X-Linked

CILD36

Ciliary Dyskinesia, Primary, 36, With Or Without Situs Inversus

Primary Ciliary Dyskinesia 36

X-Linked Primary Ciliary Dyskinesia 36
Ciliary Dyskinesia, Primary, 28

Primary Ciliary Dyskinesia 28

CILD28

Primary Ciliary Dyskinesia 28 With Or Without Situs Inversus

Ciliary Dyskinesia, Primary, 28, With Or Without Situs Inversus

Ciliary Dyskinesia, Primary, 28, Without Situs Inversus

Dyskinesia, Ciliary, Primary, 28
Kartagener Syndrome

Kartagener'S Syndrome
Visceral Heterotaxy

Situs Ambiguus

Heterotaxia

Heterotaxy Syndrome

Heterotaxy

Lateralization Defect

Situs Ambiguous

Left Isomerism

Htx

Ivemark Syndrome

Right Isomerism

Situs Ambiguus Viscerum

Incomplete Situs Inversus

Partial Situs Inversus

Heterotaxy, Visceral

Asplenia Syndrome

Bilateral Left-Sidedness

Polysplenia Syndrome

Moller Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03852 DNAH7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DNAH7 VGNC VGNC:49725
Felis catus DNAH7 VGNC VGNC:107525
Bos taurus DNAH7 VGNC VGNC:50052
Rattus norvegicus DNAH7 RGD RGD:621798
Macaca mulatta DNAH7 VGNC VGNC:71859