TXNL1 - thioredoxin like 1 Gene

Homo sapiens

Also known as Txl; TXNL; TRP32; TXL-1; HEL-S-114

Gene ID: 9352 | Gene type: protein coding

About TXNL1

Cytogenetic location: 18q21.31 Genomic coordinates (GRCh38): 18:56,597,209-56,638,592 (from NCBI)

This gene has 11 transcripts (splice variants), 217 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 57.8), testis (RPKM 14.4) and 25 other tissues.

Summary

Enables disulfide oxidoreductase activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

TXNL1 Products(1)

mRNA	Protein	Name
NM_004786.3	NP_004777.1	thioredoxin-like protein 1

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables disulfide oxidoreductase activity	IDA IDA: Inferred from direct assay	9668102	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	9668102	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TXNL1 Protein Structure

Thioredoxin

PITH

0
100
200
289 a.a.

Protein Preferred Names

Protein Names

thioredoxin-like protein 1

32 kDa thioredoxin-related protein

TXNL1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82567	Thioredoxin Like Protein 1 Antibody (YA2312)	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat

Related Diseases

Diseases

Alias

Human Monocytic Ehrlichiosis

Ehrlichiosis Chafeensis	Hme
Human Ehrlichial Infection, Human Monocytic Type

Dracunculiasis

Guinea Worm Disease	Dracontiasis
Dracunculosis	Infection By Dracunculus Medinensis
Gwd	Guinea Worm Infection
Parasitic Infection Caused By Dracunculus Medinensis	Medina Worm Disease
Medinensis	Medina Worm Infestation
Dracunculus Medinensis Infestation	Guinea Worm Infestation

Ehrlichiosis

Human Ehrlichiosis	He
Hey

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15296	TXNL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TXNL1	VGNC	VGNC:66731
Mus musculus	TXNL1	MGD	MGI:1860078
Bos taurus	TXNL1	VGNC	VGNC:36542
Rattus norvegicus	TXNL1	RGD	RGD:621717
Macaca mulatta	TXNL1	VGNC	VGNC:82264
Canis familiaris	TXNL1	VGNC	VGNC:48018

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