2. Stem Cell/Wnt TGF-beta/Smad
  3. Organoid TGF-beta/Smad
  4. IDE 2

IDE2 is a small molecule cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) by activating the TGF-βsignaling pathway.

For research use only. We do not sell to patients.

IDE 2 Chemical Structure

IDE 2 Chemical Structure

CAS No. : 1136466-93-7

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1 mg USD 76 In-stock
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Based on 1 publication(s) in Google Scholar

IDE 2 Related Antibodies

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Description

IDE2 is a small molecule cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) by activating the TGF-βsignaling pathway[1].

Molecular Weight

240.30

Formula

C12H20N2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCCCCC(O)=O)N/N=C1CCCC/1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (104.04 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1615 mL 20.8073 mL 41.6146 mL
5 mM 0.8323 mL 4.1615 mL 8.3229 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.00%

COA (242 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1615 mL 20.8073 mL 41.6146 mL 104.0366 mL
5 mM 0.8323 mL 4.1615 mL 8.3229 mL 20.8073 mL
10 mM 0.4161 mL 2.0807 mL 4.1615 mL 10.4037 mL
15 mM 0.2774 mL 1.3872 mL 2.7743 mL 6.9358 mL
20 mM 0.2081 mL 1.0404 mL 2.0807 mL 5.2018 mL
25 mM 0.1665 mL 0.8323 mL 1.6646 mL 4.1615 mL
30 mM 0.1387 mL 0.6936 mL 1.3872 mL 3.4679 mL
40 mM 0.1040 mL 0.5202 mL 1.0404 mL 2.6009 mL
50 mM 0.0832 mL 0.4161 mL 0.8323 mL 2.0807 mL
60 mM 0.0694 mL 0.3468 mL 0.6936 mL 1.7339 mL
80 mM 0.0520 mL 0.2601 mL 0.5202 mL 1.3005 mL
100 mM 0.0416 mL 0.2081 mL 0.4161 mL 1.0404 mL
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IDE 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IDE 21136466-93-7IDE2IDE-2OrganoidTGF-beta/SmadTransforming growth factor betaInhibitorinhibitorinhibit

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