Kulinone

Cat. No.: HY-116038: FAQs
Data Sheet Handling Instructions

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Kulinone has cytotoxic effects against A549, H460 and HGC27 with IC₅₀ values of 6.2 ± 0.1, 7.8 ± 1.2, 5.6 ± 0.2 μg/ml。

For research use only. We do not sell to patients.

Kulinone Chemical Structure

CAS No. : 21688-61-9

Size	Stock
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31

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This product is a controlled substance and not for sale in your territory.

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Biological Activity
Purity & Documentation
References
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Description

Kulinone has cytotoxic effects against A549, H460 and HGC27 with IC₅₀ values of 6.2 ± 0.1, 7.8 ± 1.2, 5.6 ± 0.2 μg/ml^[1]。

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	42.5 μg/mL Compound: 13	Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay	[PMID: 20961091]
U2OS	IC₅₀	6.9 μg/mL Compound: 13	Cytotoxicity against human U2OS cells after 36 hrs by MTT assay Cytotoxicity against human U2OS cells after 36 hrs by MTT assay	[PMID: 20961091]

Molecular Weight

440.70

Formula

C₃₀H₄₈O₂

CAS No.

21688-61-9

SMILES

C[C@@]12C3=CC[C@](C(C)(C(CC4)=O)C)([H])[C@@]4(C)[C@@]3([H])CC[C@]1([C@]([C@H](C2)O)([H])[C@H](C)CC/C=C(C)\C)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wu SB, et al. Cytotoxic triterpenoids and steroids from the bark of Melia azedarach. Planta Med. 2011;77(9):922-928. [Content Brief]

Kulinone Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kulinone21688-61-9OthersInhibitorinhibitorinhibit

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