2. Academic Validation
  3. Tetramic acid analogues produced by coculture of Saccharopolyspora erythraea with Fusarium pallidoroseum

Tetramic acid analogues produced by coculture of Saccharopolyspora erythraea with Fusarium pallidoroseum

  • J Nat Prod. 2014 Jan 24;77(1):173-7. doi: 10.1021/np400761g.
James Whitt 1,  Suzanne M Shipley,  David J Newman,  Karina M Zuck
Affiliations

Affiliation

  • 1 SAIC-Frederick, Inc., Frederick National Laboratory for Cancer Research , P.O. Box B, Frederick, Maryland 21702, United States.
PMID: 24422636 DOI: 10.1021/np400761g
Abstract

Coculture of the fungus Fusarium pallidoroseum with the bacterium Saccharopolyspora erythraea was found to produce three new decalin-type tetramic acid analogues related to equisetin. The structures were determined by spectroscopic methods. The absolute configurations were established by circular dichroism spectroscopy and comparing the data with those of equisetin.

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