2. Academic Validation
  3. The aurachins, new quinoline antibiotics from myxobacteria: production, physico-chemical and biological properties

The aurachins, new quinoline antibiotics from myxobacteria: production, physico-chemical and biological properties

  • J Antibiot (Tokyo). 1987 Mar;40(3):258-65. doi: 10.7164/antibiotics.40.258.
B Kunze,  G Höfle,  H Reichenbach
PMID: 3106289 DOI: 10.7164/antibiotics.40.258
Abstract

The aurachins, new Quinoline Alkaloids, were extracted with acetone from the biomass of the myxobacterium, Stigmatella aurantiaca strain Sg a15 and purified by column chromatography. The four described aurachins A, B, C and D, were inhibitory for Gram-positive bacteria and a few yeasts and molds. They blocked NADH oxidation in beef heart submitochondrial particles.

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