Olinone

Cat. No.: HY-100670: FAQs
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Olinone is a selective BRD4 BrD1 inhibitor. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation.

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Olinone Chemical Structure

CAS No. : 1770789-37-1

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Description	Olinone is a selective BRD4 BrD1 inhibitor^[1]. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation^[2].
Molecular Weight	299.37
Formula	C₁₇H₂₁N₃O₂
CAS No.	1770789-37-1
SMILES	CC(NCCCCN1C(CCN2)=C(C2=O)C3=C1C=CC=C3)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Rodríguez Y, et al. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4. Proteins. 2020 Mar;88(3):414-430. [Content Brief] [2]. Gacias M, et al. Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. Chem Biol. 2014 Jul 17;21(7):841-854. [Content Brief]

Olinone Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Olinone1770789-37-1Epigenetic Reader DomainInhibitorinhibitorinhibit

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Olinone

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