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Results for "

2'-RIBOTAC-U

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162504

    SARS-CoV Infection
    2'-RIBOTAC-U is a ribonuclease (RNase) targeting chimeras (RIBOTACs) and SARS-CoV-2 replication inhibitor. 2'-RIBOTAC-U is composed of a metabolic handle (Blue), a linker (Black) and a RNase L recruiter (Pink). RIBOTACs recruits cellular RNases to specific RNA targets, thereby leading to the degradation of these RNAs .
    2'-RIBOTAC-U
  • HY-162507

    Biochemical Assay Reagents Infection
    2'-RIBOTAC-U recruiter-linker (Compound 9) consists of RNase L recruiter and linker. 2'-RIBOTAC-U recruiter-linker is reacted separately with 2’-azido-uridine or 5’-azidomethyl-uridine via copper-catalyzed click chemistry, resulting in the formation of 2’-RIBOTAC-U and 5’-RIBOTAC-U, respectively. 2’-RIBOTAC-U has anti-SARS-CoV-2 activity .
    2'-RIBOTAC-U recruiter-linker

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