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Results for "

DUSP6

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115502A
    BCI hydrochloride
    Maximum Cited Publications
    10 Publications Verification

    (E)-BCI hydrochloride

    		 Phosphatase Inflammation/Immunology
    BCI ((E)-BCI) hydrochloride is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI hydrochloride shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI hydrochloride can be used in inflammatory disease research .
    BCI hydrochloride
  • HY-115502
    BCI
    Maximum Cited Publications
    10 Publications Verification

    (E)-BCI

    		 Phosphatase Inflammation/Immunology
    BCI ((E)-BCI) is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research .
    BCI
  • HY-RS04067
    DUSP6 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    DUSP6 Human Pre-designed siRNA Set A contains three designed siRNAs for DUSP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DUSP6 Human Pre-designed siRNA Set A
    DUSP6 Human Pre-designed siRNA Set A
  • HY-126390
    (E/Z)-BCI

    NSC 150117

    		 Phosphatase Apoptosis Inflammation/Immunology Cancer
    (E/Z)-BCI (NSC 150117) is a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory activities. (E/Z)-BCI attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-κB pathway .
    (E/Z)-BCI
  • HY-168012
    Pan-RAS-IN-6

    		Ras Phosphatase Cancer
    Pan-RAS-IN-6 (compound 24) is an inhibitor targeting DUSP6, which reduces MAPK activation in the brain of the NCI-H1373-Luc model (DUSP6), at the same time, it shows significant tumor growth inhibition and tumor regression effects in the NSCLC brain metastasis mouse model. Pan-RAS-IN-6 shows high selectivity and strong inhibitory effects, especially in KRAS mutation-related signaling pathways, demonstrating varying inhibitory activity against different KRAS mutants and interacting proteins. The IC50 values for KRAS G12C, G12D, and G12V are 1.3 nM, 4.7 nM, and 0.3 nM, respectively .
    Pan-RAS-IN-6

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