DUSP6 Antibody (YA2280)

DUSP6 Antibody (YA2280) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2280), targeting DUSP6, with a predicted molecular weight of 42 kDa (observed band size: 42 kDa). DUSP6 Antibody (YA2280) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

The protein encoded by The related gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. The related gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of The family, is localized in the cytoplasm. Mutations in The related gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for The related gene.

1848

Predicted band size: 42 kDa; Observed band size: 42 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q16828

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100

WB, IHC-P, ICC/IF, IP, FC

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human DUSP6