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NF-α

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By Targets:	NF-κB (1) p38 MAPK (1)
By Research Areas:	Cancer (1)

1

Inhibitors & Agonists

1

Recombinant Proteins

Targets Recommended: NF-κB

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

NF-κB/MAPK-IN-2	NF-κB p38 MAPK	Cancer
NF-κB/MAPK-IN-2 (compound 14) is a potent *NF-κB* and MAPK Inhibitor. NF-κB/MAPK-IN-2 decreases the protein expression of p-p65, p-IκB, p-p38, p-JNK, and p-ERK. NF-κB/MAPK-IN-2 reduces the LPS-induced release of TNF-α and IL-6. NF-κB/MAPK-IN-2 inhibits nuclear translocation of p65 and c-Fos. NF-κB/MAPK-IN-2 has the potential for the research of sepsis .

Cat. No.	Compare	Product Name	Species	Source

	TNF-alpha/TNFSF2 Protein, Human (HEK293, His) NF-alpha; TNF; TNFA; Tumor necrosis factor	Human	HEK293
	TNF-α/TNFSF2 protein is a macrophage-secreted cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR, inducing tumor cell death and acting as a pyrogen. It is associated with cachexia and stimulates cell proliferation and differentiation. TNF-alpha/TNFSF2 Protein, Human (HEK293, His) is the recombinant human-derived TNF-alpha/TNFSF2 protein, expressed by HEK293 , with C-His labeled tag. The total length of TNF-alpha/TNFSF2 Protein, Human (HEK293, His) is 157 a.a., with molecular weight of ~17 kDa.

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