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ProteinKinaseC (19-31), a peptide inhibitor of proteinkinaseC (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as proteinkinaseCsubstrate peptide for testing the proteinkinaseC activity .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) acetate is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg acetate is a substrate of EGF receptor proteinkinaseC and can be used to measure proteinkinaseC activity .
Casein Kinase 2 Substrate Peptide is a common CK2substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for proteinkinase CK2 activity determination .
ProteinkinaseCsubstrate is a substrate of ProteinkinaseC, can be used to detect protein. ProteinkinaseC is a key regulatory element in signal transduction and exerts its effects by catalysing specific substrate phosphorylation .
ProteinKinaseC Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. ProteinKinaseC Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of proteinkinaseC from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of proteinkinaseC .
ProteinKinaseC (19-31) TFA, a peptide inhibitor of proteinkinaseC (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as proteinkinaseCsubstrate peptide for testing the proteinkinaseC activity .
[Ser25] ProteinKinaseC (19-31) is a substrate of proteinkinaseC (PKC) (Km: 0.3 μM). [Ser25] ProteinKinaseC (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine .
ProteinKinaseC (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. ProteinKinaseC (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive .
p60c-src Substrate is an efficient and specific substrate for p60c-srcprotein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by proteinkinaseC (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of proteinkinaseC .
Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent proteinkinase, casein kinases I and II, Ca 2+/calmodulin-dependent proteinkinase II, or phosphorylase kinase, and can be routinely used for the assay of proteinkinaseC with low background in the crude tissue extracts .
Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent proteinkinase, casein kinases I and II, Ca 2+/calmodulin-dependent proteinkinase II, or phosphorylase kinase, and can be routinely used for the assay of proteinkinaseC with low background in the crude tissue extracts .
Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (proteinkinaseC) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering proteinkinases or phosphatases .
MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinasesubstrate (MARCKS). MPSD can sense membrane curvature and recognize phosphatidylserine. MPSD can be utilized as biological probe to study membrane shape and lipid composition .
(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of?PDK1. PIF: The proteinkinaseC-related kinase 2 (PRK2)-interacting fragment .
MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD (HY-P10471). MPSD TFA is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinasesubstrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition .
Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC50s=4-9 nM) and ζ (IC50=150 nM). Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein (CREB) and myristoylated alanine-rich Ckinasesubstrate (MARCKS). Balanol can be isolated from the fungus Verticillium balanoides .
ProteinKinaseC (19-31), a peptide inhibitor of proteinkinaseC (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as proteinkinaseCsubstrate peptide for testing the proteinkinaseC activity .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) acetate is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg acetate is a substrate of EGF receptor proteinkinaseC and can be used to measure proteinkinaseC activity .
Casein Kinase 2 Substrate Peptide is a common CK2substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for proteinkinase CK2 activity determination .
ProteinkinaseCsubstrate is a substrate of ProteinkinaseC, can be used to detect protein. ProteinkinaseC is a key regulatory element in signal transduction and exerts its effects by catalysing specific substrate phosphorylation .
ProteinKinaseC Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. ProteinKinaseC Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of proteinkinaseC from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of proteinkinaseC .
ProteinKinaseC (19-31) TFA, a peptide inhibitor of proteinkinaseC (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as proteinkinaseCsubstrate peptide for testing the proteinkinaseC activity .
[Ser25] ProteinKinaseC (19-31) is a substrate of proteinkinaseC (PKC) (Km: 0.3 μM). [Ser25] ProteinKinaseC (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine .
ProteinKinaseC (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. ProteinKinaseC (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive .
p60c-src Substrate is an efficient and specific substrate for p60c-srcprotein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
S6(229-239) is a biological active peptide. (This is a synthetic peptide substrate for S6 kinase shown to be phosphorylated by proteinkinasec with phosphorylation site identified at Ser235)
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by proteinkinaseC (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of proteinkinaseC .
Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent proteinkinase, casein kinases I and II, Ca 2+/calmodulin-dependent proteinkinase II, or phosphorylase kinase, and can be routinely used for the assay of proteinkinaseC with low background in the crude tissue extracts .
Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent proteinkinase, casein kinases I and II, Ca 2+/calmodulin-dependent proteinkinase II, or phosphorylase kinase, and can be routinely used for the assay of proteinkinaseC with low background in the crude tissue extracts .
Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (proteinkinaseC) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering proteinkinases or phosphatases .
MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich proteinkinaseCsubstrateprotein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) .
MPSD (MARCKS-ED) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinasesubstrate (MARCKS). MPSD can sense membrane curvature and recognize phosphatidylserine. MPSD can be utilized as biological probe to study membrane shape and lipid composition .
MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD (HY-P10471). MPSD TFA is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinasesubstrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition .
Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC50s=4-9 nM) and ζ (IC50=150 nM). Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein (CREB) and myristoylated alanine-rich Ckinasesubstrate (MARCKS). Balanol can be isolated from the fungus Verticillium balanoides .
The PACSIN2 protein coordinates caveolar morphogenesis and endocytosis to dynamically regulate cell membrane structure. As a lipid-binding protein, PACSIN2 regulates phosphatidic acid-containing membranes. PACSIN2 Protein, Human (HEK293, His) is the recombinant human-derived PACSIN2 protein, expressed by HEK293 , with C-6*His labeled tag.
The PACSIN1 protein has multiple functions in cell dynamics, reorganizing microtubules and the actin cytoskeleton. PACSIN1 interacts with MAPT, reduces microtubule stability and inhibits MAPT-induced polymerization. PACSIN1 Protein, Human (HEK293, His) is the recombinant human-derived PACSIN1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PACSIN1 Protein, Human (HEK293, His) is 444 a.a., with molecular weight of ~52.0 kDa.
neurogranin (Proteinkinase C substrate; RC3); RC3; hng
WB, IHC-F, IHC-P, ICC/IF, IP
Human, Mouse, Rat
Neurogranin Antibody (YA1383) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1383), targeting Neurogranin, with a predicted molecular weight of 8 kDa (observed band size: 14-16 kDa). Neurogranin Antibody (YA1383) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.
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![[Ser25] Protein Kinase C (19-31)](http://file.medchemexpress.eu/product_pic/hy-p1088.gif)
![[Ala9,10, Lys11,12] Glycogen Synthase (1-12)](http://file.medchemexpress.eu/product_pic/hy-p3741.gif)
