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SDH-IN-17

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-159481
    SDH-IN-17

    		Succinate Dehydrogenase Fungal Infection Inflammation/Immunology
    SDH-IN-17 (compound C32), a hydrazide-containing flavonol derivative, is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 8.42 μM. SDH-IN-17 can occupy the active site and form strong interactions with the key residues of SDH. SDH-IN-17 exhibits antifungal activity against Rhizoctonia solani (EC50=0.170 μg/mL). SDH-IN-17 disrupts the normal growth of hyphae by affecting the structural integrity of the cell membrane and cellular respiration. SDH-IN-17 has the potential for plant disease control research .
    SDH-IN-17

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