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SIRT6-IN-4

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170402
    SIRT6-IN-4

    		Sirtuin Apoptosis Cancer
    SIRT6-IN-4 (Compound 10d) is a selective inhibitor for SIRT6 with an IC50 of 5.68 μM. SIRT6-IN-4 inhibits the proliferation of MCF-7 with an IC50 of 8.30 μM. SIRT6-IN-4 arrests the cell cycle at G2/M phase, inhibits thecell migration and invasion of MCF-7, and induces apoptosis. SIRT6-IN-4 exhibits antitumor efficacy in mouse models .
    SIRT6-IN-4

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