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Results for "

Serotonin 5-HT uptake transporter

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

4

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107128
    Ampreloxetine hydrochloride

    TD-9855 hydrochloride

    		 Serotonin Transporter Neurological Disease
    Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma .
    Ampreloxetine hydrochloride
  • HY-N0740
    Jatrorrhizine chloride
    1 Publications Verification

    		 Cholinesterase (ChE) 5-HT Receptor Bacterial Neurological Disease Inflammation/Immunology
    Jatrorrhizine chloride is an alkaloid isolated from?Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine chloride is a potent and orally active inhibitor of?AChE?(IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
    Jatrorrhizine chloride
  • HY-N0749A
    Jatrorrhizine hydroxide
    1 Publications Verification

    		 Cholinesterase (ChE) 5-HT Receptor Bacterial Neurological Disease Inflammation/Immunology
    Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
    Jatrorrhizine hydroxide
  • HY-129985
    Clovoxamine

    DU23811

    		 Serotonin Transporter 5-HT Receptor Neurological Disease
    Clovoxamine (DU23811) (Compound 35) has binding affinity for serotonin transporter (SERT) (Ki: 61 nM). Clovoxamine is a 5-HT and norepinephrine reuptake (NE) re-uptake inhibitor. Clovoxamine is an antidepressant .
    Clovoxamine
  • HY-N0749
    Jatrorrhizine

    		Cholinesterase (ChE) 5-HT Receptor Bacterial Neurological Disease
    Jatrorrhizine is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
    Jatrorrhizine
  • HY-N0740R
    Jatrorrhizine chloride (Standard)

    		Cholinesterase (ChE) 5-HT Receptor Bacterial Neurological Disease Inflammation/Immunology
    Jatrorrhizine (chloride) (Standard) is the analytical standard of Jatrorrhizine (chloride). This product is intended for research and analytical applications. Jatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
    Jatrorrhizine chloride (Standard)