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Pathways Recommended:	Metabolic Enzyme/Protease

Results for "

Trypsin-like serine protease

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ser/Thr Protease (5) Biochemical Assay Reagents (1) Caspase (1) Fluorescent Dye (2)
By Research Areas:	Cancer (4) Inflammation/Immunology (1)

8

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

5

Recombinant Proteins

Targets Recommended: Ser/Thr Protease Virus Protease HCV Protease HIV Protease Protease Activated Receptor (PAR) Serpin Polo-like Kinase (PLK) NOD-like Receptor (NLR) Toll-like Receptor (TLR) MASTL C-type Lectin-like Receptor (CTLR) Enteropeptidase SRPK SHMT ClpP STK33 ASCT KLF ANGPTL PERK ULK METTL3 ADAMTS IGF-1R LOX-1 Nuclear Hormone Receptor 4A/NR4A FLT3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Boc-Val-Pro-Arg-AMC hydrochloride	Fluorescent Dye	Others
Boc-Val-Pro-Arg-AMC hydrochloride is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

Benzamidine hydrochloride 2 Publications Verification	Ser/Thr Protease	Cancer
Benzamidine hydrochloride is a **trypsin-like serine proteases with K_i*s of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin*, uPA, Factor Xa, Thrombin and tPA, respectively .

Benzamidine hydrochloride hydrate 2 Publications Verification Benzenecarboximidamide hydrochloride hydrate	Ser/Thr Protease	Cancer
Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a reversible competitive **trypsin-like serine proteases inhibitor with K_i*s of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin*, uPA, Factor Xa, Thrombin and tPA, respectively .

4-Iodobenzylamine (4-Iodophenyl)methanamine	Biochemical Assay Reagents	Others
4-Iodobenzylamine ((4-Iodophenyl)methanamine) is a probe that can detect the binding patterns of serine proteases that are like trypsin, as well as urokinase-type plasminogen activator (uPA). 4-Iodobenzylamine is stable in aqueous solution .

Boc-Val-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

UAMC-00050	Ser/Thr Protease	Inflammation/Immunology
UAMC-00050 is a potent **trypsin-like serine protease** inhibitor. UAMC-00050 can be used in research of dry eye syndrome and ocular inflammation .

APC-6860	Ser/Thr Protease	Cancer
APC-6860 is a **trypsin-like serine proteases inhibitor with k_i** values of 0.21 and 0.44 μM for uPA and trypsin, respectively. APC-6860 has a selectivity ratio for tPA versus uPA of 80. APC-6860 has k_i values of 0.1 and 0.082 μM for human and murine urokinases, respectively. APC-6860 can be used for the research of cancer .

N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride TLCK hydrochloride	Caspase Ser/Thr Protease	Cancer
N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK hydrochloride) is an irreversible inhibitor for serine protease, which inhibits trypsin and trypsin-like protease by alkylating histidine residues in their active site. N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride inhibits caspase-3, caspase-6 and caspase-7, with IC₅₀s of 12.0, 54.5 and 19.3 μM, respectively. N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride induces apoptosis in cell HL-60, and inhibits the decrease in mitochondrial transmembrane potential during apoptosis .

Cat. No.	Product Name	Type

Benzamidine hydrochloride hydrate 2 Publications Verification Benzenecarboximidamide hydrochloride hydrate	Biochemical Assay Reagents
Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a reversible competitive **trypsin-like serine proteases inhibitor with K_i*s of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin*, uPA, Factor Xa, Thrombin and tPA, respectively .

Cat. No.	Product Name	Target	Research Area

Boc-Val-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

Species:	Human (4) Mouse (1)
Tag:	His (4) Tag Free (1)
Source:	HEK293 (4) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

	TMPRSS11D Protein, Human (HEK293, His) Transmembrane protease serine 11D; Airway Trypsin-like protease; HAT	Human	HEK293
	The TMPRSS11D protein is associated with host mucosal defense and acts synergistically with substances in the airway mucosa. It critically processes ACE2, activating the human coronavirus 229E spike glycoprotein to achieve virus-cell membrane fusion. TMPRSS11D Protein, Human (HEK293, His) is the recombinant human-derived TMPRSS11D protein, expressed by HEK293 , with N-His labeled tag. The total length of TMPRSS11D Protein, Human (HEK293, His) is 232 a.a., with molecular weight of ~27.6 kDa.

	Kallikrein-11 Protein, Human (Sf9) rHuKallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; serine protease 20	Human	Sf9 insect cells
	Kallikrein 11 Protein, Human (Sf9) is a possible multifunctional protease and efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin.

	Kallikrein-11 Protein, Human (HEK293, His) Kallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; serine protease 20	Human	HEK293
	Kallikrein-11 protein is suggested to be a multifunctional protease, efficiently cleaving the substrate 'bz-Phe-Arg-4-methylcoumaryl-7-amide' and showing weak cleavage activity toward other kallikrein and trypsin substrates. It predominantly cleaves synthetic peptides after arginine residues rather than lysine residues. Kallikrein-11 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-11 protein, expressed by HEK293 , with C-His labeled tag.

	Kallikrein-11 Protein, Mouse (HEK293, His) Kallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; serine protease 20	Mouse	HEK293
	Kallikrein-11 protein, a potential multifunctional protease, demonstrates efficient cleavage of the substrate 'bz-Phe-Arg-4-methylcoumaryl-7-amide,' specific to kallikrein. It also displays weaker cleavage activity toward other substrates linked to kallikrein and trypsin. This multifunctional characteristic indicates versatility in substrate recognition and cleavage, suggesting a potential role in diverse proteolytic processes. Kallikrein-11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-11 protein, expressed by HEK293 , with C-His labeled tag.

	TMPRSS11B Protein, Human (HEK293, His) Transmembrane protease serine 11B; Airway Trypsin-like protease 5; TMPRSS11B; HATL5	Human	HEK293
	TMPRSS11B, a serine protease, is susceptible to inhibition by aprotinin, leupeptin, benzamidine, SERPINA1, SPINT1, and SPINT2, highlighting its susceptibility to various regulatory mechanisms. TMPRSS11B Protein, Human (HEK293, His) is the recombinant human-derived TMPRSS11B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TMPRSS11B Protein, Human (HEK293, His) is 378 a.a., with molecular weight of ~61.0 kDa.

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