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fungus metabolite

" in MedChemExpress (MCE) Product Catalog:

40

Inhibitors & Agonists

35

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119663

    Fungal Infection
    Averantin is the minor metabolite of the fungus Cercospora arachidicola . Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway .
    Averantin
  • HY-N8552

    Endogenous Metabolite Infection
    Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus .
    Banksialactone A
  • HY-N10299

    Endogenous Metabolite Infection
    Guignardone J is the secondary metabolite isolated from endophytic fungus Phyllosticta capitalensis .
    Guignardone J
  • HY-113622

    Palmarumycin C13; Diepoxin ζ; Antibiotic Sch53514

    Fungal Antibiotic Infection
    Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations .
    Cladospirone bisepoxide
  • HY-N8846

    Fungal Infection
    dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .
    dl-Aloesol
  • HY-N10235

    Endogenous Metabolite Others
    Tajixanthone is the fungus metabolite from Aspergillus variecolor .
    Tajixanthone
  • HY-119328

    Endogenous Metabolite Others
    Pestalotin, a fungal lactone, is a secondary metabolite of endophytic fungus Pestalotiopsis microspore .
    Pestalotin
  • HY-129515

    Fungal Others
    Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride .
    Trichodecenin II
  • HY-170738

    Tryptophan Hydroxylase Neurological Disease
    CAY10799 potassium is a derivative of Oudenone. Oudenone, a metabolite of the fungus, is a catecholamine biosynthesis and tyrosine hydroxylases inhibitor .
    CAY10799 potassium
  • HY-125706

    Fungal Antibiotic Infection
    1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .
    1233B
  • HY-N12194

    Others Infection
    Cytochalasin O (compound 13) is a secondary metabolite of the phytopathogenic fungus P. sp. CIB-109 .
    Cytochalasin O
  • HY-N7023

    7-O-Prenylumbelliferone

    Fungal Infection
    7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense .
    7-Prenyloxycoumarin
  • HY-N10301

    Toll-like Receptor (TLR) Infection
    Guignardone L is a metabolite isolated from the endophytic fungus Guignardia mangiferae with toll-like receptor 3 regulating activity .
    Guignardone L
  • HY-121395

    Antibiotic Fungal Infection
    Lepiochlorin is an antibiotic metabolite produced by a fungus (Lepiota species) that is cultivated by ants, which can prevent fungal contamination .
    Lepiochlorin
  • HY-N10262

    Endogenous Metabolite Others
    Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .
    Piliformic acid
  • HY-B1086

    N-Acetyl-DL-phenylalanine

    Endogenous Metabolite Neurological Disease
    Afalanine (N-Acetyl-DL-phenylalanine) is an endogenous metabolite of an endophytic fungus with antidepressant activity. Afalanine can be used in combination with antibiotics to prevent renal damage.
    Afalanine
  • HY-W017445

    Fungal Infection
    Homogentisic acid lactone (Compound 1) is a fungal metabolite with fungicidal activity, which is found in the fungus WF5. Homogentisic acid lactone is active against the plant pathogenic fungus F. graminearum. Homogentisic acid lactone can be used as a substrate in the determination of serum paraoxonase/arylesterase 1 (PON1) activity .
    Homogentisic acid lactone
  • HY-N10289

    Fungal Infection
    Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .
    Cytosporone C
  • HY-119821

    Glycosidase Infection
    Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has significant α-glucosidase inhibitory activity .
    Terphenyllin
  • HY-N12893

    Fungal Lipase Infection
    Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM) .
    Sclerodione
  • HY-122474

    Others Cancer
    Acetylaranotin is a metabolite produced by the fungus Arachniotus aureus, exhibiting antitumor activity. Acetylaranotin is utilized in research within the field of oncology for its potential in anti-cancer applications .
    Acetylaranotin
  • HY-N12179

    Bacterial Others
    Brevianamide M (compound 4) is a metabolite of Aspergillus versicolor. This is an endophytic fungus isolated from the marine brown alga Sargassum. Brevianamide M has antimicrobial activity against Escherichia coli and Staphylococcus aureus .
    Brevianamide M
  • HY-N7569

    Apoptosis Caspase PPAR Cancer
    Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage .
    Demethoxyfumitremorgin C
  • HY-N13021

    Endogenous Metabolite Others
    2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid is a metabolite, which can be isolated from endophytic fungus Phoma macrostoma inhabiting the inner tissue of medicinal plant Glycyrrhiza glabra Linn .
    2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid
  • HY-N8511

    Fungal Infection
    Acremine I is a fungi inhibitor and also a metabolite of the endophytic fungus Acremonium byssoides. Acremine I can effectively inhibit Plasmopara viticola. Acremine I can be used for research on plant diseases, such as grape downy mildew .
    Acremine I
  • HY-N10184

    FKI-0550

    Others Infection
    Paecilaminol (FKI-0550) is potent NADH-fumarate reductase inhibitor. Paecilaminol exhibits an IC50 value of 5.1 μM against Ascaris suum NADH-fumarate reductase .
    Paecilaminol
  • HY-75564

    Endogenous Metabolite Cancer
    Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC50 values range from 9.5 to 18.1 μM .
    Cyclo(Ala-Gly)
  • HY-N8406

    Bacterial Antibiotic Infection
    Monomethylsulochrin is a potent antibacterial metabolite from endophytic fungus Aspergillus fumigatus, isolated from Albizia lucidior leaves (fabaceae). Monomethylsulochrin exhibits anti-Staphylococcus aureus activity with minimum inhibitory concentration (MIC) of 31.25 μg/mL .
    Monomethylsulochrin
  • HY-N13024

    Fungal Infection
    Radulone A is a secondary metabolite, which can be isolated from the wood decomposing fungus Granulobasidium vellereum. Radulone A inhibits spore germination of Phlebiopsis gigantea, Coniophora puteana and Heterobasidion occidentale, with concentrations of 10 µM, 500 µM and 100 µM, respectively .
    Radulone A
  • HY-N10288

    Fungal Endogenous Metabolite Infection
    Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .
    Eucalyptacid A
  • HY-N10269

    Fungal Endogenous Metabolite Infection
    Phomalactone, produced by the fungus Nigrospora sphaerica, specifically inhibits the mycelial growth of Phytophthora infestans, with an MIC value of 2.5 mg/L . Phomalactone is phytotoxic to Z. elegans and other plant species by inhibition of seedling growth and by causing electrolyte leakage from photosynthetic tissues of both Z. elegans leaves and cucumber cotyledons .
    Phomalactone
  • HY-142088

    Endogenous Metabolite Metabolic Disease
    Beauverolide Ka, a cyclotetradepsipeptide, is a metabolite of Beauveria bassiana fungus. Beauverolide Ka stimulates glucose uptake in cultured rat L6 myoblasts at 50 μM. Beauverolide Ka exhibits protecting effects on HEI-OC1 cells at 10 μM and shows dose-dependent activity in both L6 myoblasts and myotubes .
    Beauverolide Ka
  • HY-W714837

    4-Oxo-5-phenylpentanoic acid; 5-Phenyl-4-oxopentanoic acid

    Bacterial Fungal Antibiotic Drug Intermediate Endogenous Metabolite Sigma Receptor Infection
    5-Phenyllevulinic acid (4-Oxo-5-phenylpentanoic acid) is an endogenous fungal metabolite with inhibitory activity against the bacterium B. megaterium, the plant pathogenic fungus S. tritici, and the alga C. fusca. 5-Phenyllevulinic acid is also an intermediate in the synthesis of σ receptor ligands. 5-Phenyllevulinic acid holds potential for research in the field of anti-infection studies .
    5-Phenyllevulinic acid
  • HY-N12390

    Isocitrate Dehydrogenase (IDH) Cancer
    Alternaphenol B2 is a selective IDH1 inhibitor from the coral-derived fungus Parengyodontium album SCSIO SX7W11. Alternaphenol B2 shows inhibitory activity against isocitrate dehydrogenase mutant R132H (IDH1m), with IC50 values of 41.9 μM .
    Alternaphenol B2
  • HY-N7307

    Bacterial Infection
    Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .
    Pachybasin
  • HY-N10113

    Muconomycin B

    Apoptosis Arenavirus Fungal Antibiotic Reactive Oxygen Species Infection Cancer
    Verrucarin J (Muconomycin B) is a metabolite of the Myrothecium fungus family. Verrucarin J generates reactive oxygen species (ROS) and induces apoptosis of cancer cell lines, such as A549, HCT 116 and SW-620 cells. Verrucarin J shows activities against Candida albicans and Mucor miehei. Verrucarin J inhibits arenavirus Junin (JUNV) yield with an IC50 of 1.2 ng/mL .
    Verrucarin J
  • HY-N12198

    Others Cancer
    Mollicellin H is a secondary metabolite of the fungus C. brasiliense and has a wide range of biological activities, including immunomodulation, cytotoxicity and anti-tumor effects. The growth inhibitory effects (GI50s) of Mollicellin H on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines are 5.1 μg/mL, 6.5 μg/mL and 2.5 μg/mL respectively .
    Mollicellin H
  • HY-126167

    Fungal Phosphodiesterase (PDE) Infection
    Deacetylsclerotiorin is a secondary metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7..45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM) .
    Deacetylsclerotiorin
  • HY-129432

    Fungal Phosphodiesterase (PDE) Infection
    (-)-Deacetylsclerotiorin (Compound 30) is the enantiomer of Deacetylsclerotiorin (HY-126167). Deacetylsclerotiorin is the metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7.45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM) .
    (-)-Deacetylsclerotiorin
  • HY-N12165

    Others Others
    1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .
    1,3,5,6-Tetrahydroxy-8-methylxanthone

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