1. Anti-infection
  2. Fungal
  3. Averantin

Averantin is the minor metabolite of the fungus Cercospora arachidicola. Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway.

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Averantin Chemical Structure

Averantin Chemical Structure

CAS No. : 5803-62-3

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Based on 1 publication(s) in Google Scholar

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Description

Averantin is the minor metabolite of the fungus Cercospora arachidicola[1]. Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway[2].

Cellular Effect
Cell Line Type Value Description References
MCF7 IC50
45.47 μM
Compound: 11
Cytotoxicity against human MCF7 cells after 72 hrs BY SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs BY SRB assay
[PMID: 22703109]
NCI-H460 IC50
> 50 μM
Compound: 11
Cytotoxicity against human NCI-H460 cells after 72 hrs BY SRB assay
Cytotoxicity against human NCI-H460 cells after 72 hrs BY SRB assay
[PMID: 22703109]
SF-268 IC50
> 50 μM
Compound: 11
Cytotoxicity against human SF268 cells after 72 hrs BY SRB assay
Cytotoxicity against human SF268 cells after 72 hrs BY SRB assay
[PMID: 22703109]
Molecular Weight

372.37

Formula

C20H20O7

CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C1C2=C(C=C(O)C=C2O)C(C3=CC(O)=C([C@@H](O)CCCCC)C(O)=C13)=O

Structure Classification
Initial Source

Fungi Aspergillus unguis 158SC-067 and A. flocculosus 01NT-1.1.5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 3.8 mg/mL (10.20 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6855 mL 13.4275 mL 26.8550 mL
5 mM 0.5371 mL 2.6855 mL 5.3710 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6855 mL 13.4275 mL 26.8550 mL 67.1375 mL
5 mM 0.5371 mL 2.6855 mL 5.3710 mL 13.4275 mL
10 mM 0.2686 mL 1.3428 mL 2.6855 mL 6.7138 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Averantin
Cat. No.:
HY-119663
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