2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Phosphodiesterase (PDE)
  4. Deacetylsclerotiorin

Deacetylsclerotiorin is a secondary metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7..45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM).

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Deacetylsclerotiorin Chemical Structure

Deacetylsclerotiorin Chemical Structure

CAS No. : 34696-50-9

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Deacetylsclerotiorin Related Antibodies

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Description

Deacetylsclerotiorin is a secondary metabolite of chloramphenicol isolated from the fungus Bartalinia robillardoides strain LF550. Deacetylsclerotiorin has significant inhibitory effects on Candida albicans (IC50=24 μM), Trichophyton rubrum (IC50=2.83 μM) and Septoria tritici (IC50=7..45 μM). In addition, Deacetylsclerotiorin also exhibits inhibitory effects on the enzyme phosphodiesterase 4 (PDE4) (IC50=2.8 μM)[1].

IC50 & Target[1]

PDE4

2.8 μM (IC50)

Molecular Weight

348.82

Formula

C19H21ClO4
CAS No.
SMILES

O=C1[C@](O)(C(C2=COC(/C=C/C(C)=C/[C@H](CC)C)=CC2=C1Cl)=O)C
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Purity & Documentation
References
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Deacetylsclerotiorin Related Classifications

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Keywords:

Deacetylsclerotiorin34696-50-9FungalPhosphodiesterase (PDE)Secondary metabolitesAntimicrobial activityPDE4Inhibitorinhibitorinhibit

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