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kaempferol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) AMPK (1) Apoptosis (6) Autophagy (6) Bacterial (4) Biochemical Assay Reagents (1) Cholinesterase (ChE) (1) COX (1) Endogenous Metabolite (4) Estrogen Receptor/ERR (4) FOXO (1) Glycosidase (4) GSK-3 (1) HIV (3) Influenza Virus (2) Insecticide (1) Interleukin Related (1) Mitochondrial Metabolism (2) Mitophagy (2) NF-κB (3) NO Synthase (1) p38 MAPK (1) Parasite (2) Phosphatase (1) PI3K (1) PTEN (2) Ribosomal S6 Kinase (RSK) (1) TNF Receptor (1) Toll-like Receptor (TLR) (1) Topoisomerase (1) β-catenin (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (4) Infection (6) Inflammation/Immunology (9) Metabolic Disease (11) Neurological Disease (5)

By Targets:

Akt (1)

AMPK (1)

Apoptosis (6)

Autophagy (6)

Bacterial (4)

Biochemical Assay Reagents (1)

Cholinesterase (ChE) (1)

COX (1)

Endogenous Metabolite (4)

Estrogen Receptor/ERR (4)

FOXO (1)

Glycosidase (4)

GSK-3 (1)

HIV (3)

Influenza Virus (2)

Insecticide (1)

Interleukin Related (1)

Mitochondrial Metabolism (2)

Mitophagy (2)

NF-κB (3)

NO Synthase (1)

p38 MAPK (1)

Parasite (2)

Phosphatase (1)

PI3K (1)

PTEN (2)

Ribosomal S6 Kinase (RSK) (1)

TNF Receptor (1)

Toll-like Receptor (TLR) (1)

Topoisomerase (1)

β-catenin (1)

By Research Areas:

Cancer (13)

Cardiovascular Disease (4)

Infection (6)

Inflammation/Immunology (9)

Metabolic Disease (11)

Neurological Disease (5)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14590

*Kaempferol* Maximum Cited Publications 37 Publications Verification Kempferol; Robigenin	Estrogen Receptor/ERR Autophagy Mitophagy Apoptosis HIV Parasite Endogenous Metabolite	Cancer
Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer .

HY-N7176

Kaempferol 3-O-β-D-glucuronide 2 Publications Verification kaempferol-3-glucuronide; kaempferol-3-O-glucuronide	Interleukin Related	Metabolic Disease Inflammation/Immunology Cancer
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism .

HY-107207

Kaempferol 3-neohesperidoside kaempferol 3-O-neohesperidoside	Others	Metabolic Disease
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid . Kaempferol 3-neohesperidoside exhibits insulinomimetic effect on the rat soleus muscle .

HY-N3431

Kaempferol-7-O-rhamnoside	Glycosidase	Metabolic Disease
Kaempferol-7-O-rhamnoside, isolated from Chimonanthus nitens Oliv. Leaves, is a potent α-glucosidase activity inhibitor. Kaempferol-7-O-rhamnoside has the potential for diabetes .

HY-N1789

Kaempferol-7,4'-dimethyl ether	Phosphatase Others	Others
Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM .

HY-N2054

Kaempferol 4'-glucoside kaempferol 4'-β-glucoside	Others	Others
Kaempferol 4'-glucoside (Kaempferol 4'-β-glucoside) is a flavonol glycoside.

HY-N8161

Kaempferol-3,7-di-O-β-glucoside kaempferol 3,7-diglucoside	Glycosidase Cholinesterase (ChE)	Neurological Disease
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research .

HY-107207R

Kaempferol 3-neohesperidoside (Standard)	Others	Metabolic Disease
Kaempferol 3-neohesperidoside (Standard) is the analytical standard of Kaempferol 3-neohesperidoside. This product is intended for research and analytical applications. Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid . Kaempferol 3-neohesperidoside exhibits insulinomimetic effect on the rat soleus muscle .

HY-N3430

Kaempferol tetraacetate AF33	Others	Cancer
Kaempferol tetraacetate (AF33) is a natural product. Kaempferol tetraacetate shows cytotoxicity .

HY-N9381

Kaempferol 3,4'-diglucoside	Endogenous Metabolite	Others
Kaempferol 3,4'-diglucoside is a flavonol isolated from the aqueous methanolic extract of norway spruce buds. Kaempferol 3,4'-diglucoside is identified in the needles .

HY-N2717

Kaempferol-3-O-β-D-6''-acetylglucoside kaempferol 3-O-(6''-O-acetyl)glucoside	Others	Others
Kaempferol-3-O-β-D-6 "-acetylglucoside is a flavonoid glycoside compound that can be isolated from Arnica .

HY-N10776

Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside	HIV	Infection
Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside is a glucopyranoside. Kaempferol-3-O-(6′′-galloyl)-β-glucopyranoside inhibts HIV-2 RNase H with an IC₅₀ value of 5.19 μM .

HY-N0208

Kaempferol-3-O-glucorhamnoside	p38 MAPK NF-κB	Inflammation/Immunology
Kaempferol-3-O-glucorhamnoside, a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo .

HY-N1510R

Kaempferol 3-O-gentiobioside (Standard)	Glycosidase	Metabolic Disease
Kaempferol 3-O-gentiobioside (Standard) is the analytical standard of Kaempferol 3-O-gentiobioside. This product is intended for research and analytical applications. Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. Kaempferol 3-O-gentiobioside possesses activity against α-glucosidase and displays carbohydrate enzyme inhibitory effect with an IC₅₀ of 50.0 μM .

HY-14590R

Kaempferol (Standard) Kempferol(Standard); Robigenin (Standard)	Estrogen Receptor/ERR Autophagy Mitophagy Apoptosis HIV Parasite Endogenous Metabolite	Cancer
Kaempferol (Standard) is the analytical standard of Kaempferol. This product is intended for research and analytical applications. Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer .

HY-N3433

Kaempferol 3-O-arabinoside 1 Publications Verification	Others	Others
Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity .

HY-N2055

Kaempferol 3-O-sophoroside	Toll-like Receptor (TLR) NF-κB TNF Receptor AMPK	Neurological Disease Inflammation/Immunology
Kaempferol 3-O-sophoroside is an orally active derivative of Kaempferol. It exhibits anti-inflammatory, analgesic, and antidepressant effects. Kaempferol 3-O-sophoroside is an inhibitor of the cell surface receptor toll-like receptor (TLR) 2/4 for High mobility group box 1 (HMGB1), and it also exerts anti-inflammatory effects by blocking the activation of NF-κB expression and the production of TNF-α. Kaempferol 3-O-sophoroside promotes the production of brain-derived neurotrophic factor (BDNF) and enhances autophagy by binding to AMP-activated protein kinase (AMPK), thereby exerting antidepressant effects. Kaempferol 3-O-sophoroside holds promise for research in the fields of inflammation and neurodegenerative diseases .

HY-N1510

Kaempferol 3-O-gentiobioside	Glycosidase	Metabolic Disease
Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. Kaempferol 3-O-gentiobioside possesses activity against α-glucosidase and displays carbohydrate enzyme inhibitory effect with an IC₅₀ of 50.0 µM .

HY-N0627

Kaempferol-7-O-β-D-glucopyranoside	Others	Inflammation/Immunology
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid isolated from Malus pumila Mill. flowers, has antioxidative, anti-inflammatory and procoagulant activitives .

HY-N11702

Kaempferol-3-O-robinoside-7-O-glucoside	Others	Others
Kaempferol-3-O-robinoside-7-Oglucoside is a double-chain flavonol triglycoside can be extracted from Withania somnifera .

HY-N13596

Kaempferol 3,5-dimethyl ether	Others
Kaempferol 3,5-dimethyl ether is a natural product .

HY-N2226

Kaempferol 3-sophoroside 7-rhamnoside	Others	Others
Kaempferol 3-sophoroside 7-rhamnoside acts as a potential biomarker .

HY-N8877

Kaempferol 3-O-rhamninoside	Others	Others
Kaempferol 3-O-rhamninoside is a Flavonoids product that can be isolated from the seeds of Patrinia villosa (Thunb.) Juss. .

HY-N8954

Kaempferol 7-O-neohesperidoside	Others	Cancer
Kaempferol 7-O-neohesperidoside is a ?avonoid glycoside that can be isolated from Litchi chinensis. Kaempferol 7-O-neohesperidoside exhibits significant cytotoxic activity against A549, LAC, Hep-G2, and HeLa cell lines with IC₅₀s of 0.53, 7.93, 0.020, and 0.051 μM, respectively .

HY-N2938

Biorobin kaempferol 3-O-robinobioside	Others	Cancer
Biorobin (Kaempferol 3-O-robinobioside), a flavonoid, significantly inhibits the human lymphocyte proliferation in vitro .

HY-N6605

Kaempferol 3-O-β-D-galactopyranoside 1 Publications Verification Trifolin	Apoptosis	Cardiovascular Disease Cancer
Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects .

HY-N6965

Kaempferol-3-O-(6'''-trans-p-coumaroyl-2''-glucosyl)rhamnoside	Others	Metabolic Disease
Kaempferol-3-O-(6'''-trans-p-coumaroyl-2''-glucosyl)rhamnoside is a natural antioxidant from herbal medicines .

HY-N3435

Kaempferol 3,4',7-triacetate	Others	Others
Kaempferol 3,4',7-triacetate is a natural compound isolated from bud exudate of Gardenia urvillei and Gardenia oudiepe .

HY-N5117

Kaempferol 3-sophoroside-7-glucoside	Others	Metabolic Disease
Kaempferol 3-sophoroside-7-glucoside is a bioactive component in roasted Lycium chinense leaves with anti-obesity activity .

HY-N5119

Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside	Others	Others
Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside is a natural glycoside that could be found in Camellia oleifera seeds .

HY-N12831

6-Methoxykaempferol 3-glucoside kaempferol-6-methoxy-3-O-β-D-glucoside	Others	Others
6-Methoxykaempferol 3-glucoside (Kaempferol-6-methoxy-3-O-β-D-glucoside) is a natural product .

HY-N10784

Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside	Insecticide	Others
Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside is a acylated keampferol glucoside. Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside can be isolated from the leaves of O. dentata, acts as a repellent against a fouling organism, the blue mussel M. edulis .

HY-N3434

Kaempferol 3,7,4'-trimethyl ether	Others	Others
Kaempferol 3,7,4'-trimethyl ether is a flavonol aglycone isolated from the leaves of Siparuna gigantotepala, has antioxidant activity .

HY-N8165

Kaempferol 3-O-rutinoside 7-O-glucoside	Others	Others
Kaempferol 3-O-rutinoside 7-O-glucoside is a flavonoid glycoside from red tomato .

HY-N11910

Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside	Biochemical Assay Reagents	Others
Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside (Compound 3) is a wound healing agent with dose-dependent wound healing ability. Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside can be used for wound repair research .

HY-N11573

Kaempferol 3,7-bis(α-L-rhamnose-D-glucose)	Others	Others
Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (compound 1) is a flavonoid glycoside that can be found in Euonymus fortune.

HY-N1441

Afzelin 4 Publications Verification kaempferol-3-O-rhamnoside	Mitochondrial Metabolism PTEN Autophagy Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .

HY-N8163

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside	Others	Others
Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is an antioxidant with an IC₅₀ of 26.6 μM (DPPH assay) .

HY-N12650

Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside	Endogenous Metabolite	Metabolic Disease
Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside (compound 42) is a flavonol that can be isolated from Platanus Occidentalis. Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside is an inhibitor of alpha-amylase and DPP IV .

HY-N7932

Kaempferol 3-O-α-L-rhamnopyranosyl(2,1)-α-L-rhamnopyranoside	Others	Others
Kaempferol 3-O-α-L-rhamnopyranosyl(2,1)-α-L-rhamnopyranoside (compound 23) is a flavonoid isolated from the whole herb of E. wushanense .

HY-N9529

Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside)	Others	Others
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside) is a flavonoid glycoside compound .

HY-N9676

Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside	Others	Others
Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside is a flavonoid compound that can be isolated from Quercus dentata. Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside suppresses the superoxide generation induced by arachidonic acid .

HY-N3476

Isokaempferide kaempferol 3-methyl ether; kaempferol 3-O-methyl ether	Others	Others
Isokaempferide is a flavonoid can be isolated from the aerial parts of Genista ephedroides .

HY-15449

Kaempferide 2 Publications Verification kaempferol 4'-O-methyl ether	Estrogen Receptor/ERR Autophagy Bacterial Influenza Virus Apoptosis PI3K Akt GSK-3 FOXO β-catenin	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research .

HY-N8167

Plantanone B kaempferol 3-O-rhamnosylgentiobioside	COX	Inflammation/Immunology
Plantanone B is a moderate antioxidant-agent with an IC₅₀ of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research .

HY-15449R

Kaempferide (Standard) kaempferol 4'-O-methyl ether (Standard)	Estrogen Receptor/ERR Autophagy Bacterial Influenza Virus Apoptosis	Infection Cancer
Kaempferide (Standard) is the analytical standard of Kaempferide. This product is intended for research and analytical applications.

HY-N0015

Astragalin 5 Publications Verification Astragaline; 3-Glucosylkaempferol; kaempferol 3-β-D-glucopyranoside	Apoptosis NF-κB	Infection Inflammation/Immunology Cancer
Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis .

HY-N1742

2''-O-Coumaroyljuglanin 2''-O-p-Cumaroyleuglanin; kaempferol 3-O-[2′′-(E)-p-coumaroyl]-α-L-arabinofuranoside	Others	Others
2''-O-Coumaroyljuglanin (2''-O-p-Cumaroyleuglanin) is a flavonoid which can be isolated from the flowers of Prunus spinosa .

HY-126422

cis-Tiliroside	Others	Cancer
cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line .

HY-N12271

Antioxidant agent-14	Others	Others
Antioxidant agent-14 is a kaempferol glycoside isolated from the leaves of Brassica juncea .

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